The QT interval is an electrocardiographic measure representing the sum of ventricular depolarization and repolarization, estimated by QRS duration and JT interval, respectively. QT interval abnormalities are associated with potentially fatal ventricular
For the molecular docking process, we employed Glide-SP and Glide-XP software,31 integrated within the VirtualFlow Unity26 (VFU) pipeline (https://github.com/VirtualFlow/VFU). In the interest of scientific inclusivity, we provide a VFU setup that utilizes QuickVina50 and Smina,51 two open-...
Ajay Kumar Saxena & Rajendra Prasad† The ABC transporter Cdr1 protein (Cdr1p) of Candida albicans, which plays a major role in antifungal resistance, has two transmembrane domains (TMDs) and two nucleotide binding domains (NBDs) that are interconnected by extracellular (ECLs) and intrace...
nci60 cancer cell line panel data and rnai analysis help identify eaf2 as a modulator of simvastatin and lovastatin response in hct-116 cellsnci60癌症细胞系面板数据和rnai分析有助于确定eaf2调制器的辛伐他汀、洛伐他汀反应hct - 116细胞 NCI60 Cancer Cell Line Panel Data and RNAi Analysis Help ...
Then, targetFinder [35] and psRopot software [36] was used to predict the target genes of these 89 DEMs. Eighteen unique target genes were predicted to be cleaved by four conserved miRNAs and nine novel miRNAs (Table S12). Interestingly, several targets were predicted to be cleaved by more...
This work was supported by the European Union’s Interreg Danube Transnational Cooperation Programme in the Danube Floodplain project—Reducing the flood risk through floodplain restoration along the Danube River and tributaries (grant number DTP2-003-2.1, 2018). Moreover, Markus Eder was supported by...