We detected more than 20 specific protein bands of various intensities in fractions bound to PCNA-fixed resin from human cell lysates and determined their peptide sequences by liquid chromatography and tandem mass spectrometry. A search with human protein data bases identified 12 reported PCNA-binding...
1C–E). To better understand the expression pattern of TJs in the TME, we utilized a GC single-cell RNA sequence dataset (GSE183904), which includes 6 DGC samples and 14 IGC samples. The single-cell RNA (scRNA) data processing procedure is illustrated in Fig. 1F and Figure S3, with ...
This paper presents a fieldwork methodology that used heat maps to identify areas prone to Violence Against Women (VAW) in the public sphere of five urban localities of the municipality of Corregidora, Querétaro in MexicoFootnote1. The heat maps were used to identify locations where women appear...
The receiver coil was a phased array surface coil for mouse brain (Bruker BioSpin, Ettlingen, Germany). We used a T2w turbo RARE fast spin-echo MRI sequence with 1 effective echo time (ET) = 33 ms, slice thickness = 0.5 mm, repetition time (TR) = 2336 ms, field of ...
1(b)). The GO MFs were mainly enriched in protein binding, flavin adenine dinucleotide binding, microtubule motor activity, ATP binding, chromatin binding, enzyme binding, RNA polymerase II core promoter proximal region sequence-specific binding, and microtubule binding (GO IDs: 0008017, 0042802, ...
Fig. 1. (A) Distribution and proportion of protein sequences coverage. (B) Venn diagrams represent the overlap of differential abundance proteins (DAPs) from the GM/LT comparison and ST/LT comparison. LT: Longissimus thoracis; GM: gluteus maximus; ST: semitendinosus. (C and D) Volcano plot...
Intriguingly, 11 of the phosphatidylinositide-binding protein fragments are from nuclear proteins, including four containing homeobox domains. We found that phosphatidylinositides and double-stranded DNA oligonucleotides derived from homeobox domain target sequences compete for binding to homeobox domain-...
Sequence fromDeath of Copra. Earlier this year, you released the landmarkCreating Copra,which, I think, took off in a way that you weren’t expecting. How hasCreating Copraand its popularity changed how you see both the comic and your audience?
Table 1. Unique peptides with experimental IC50 values from top 10 predictions Sequence IC50, µM Sequence IC50, µM AutoDock Vina PeptoGrid AWW 6.5 GAW 240.0 VWY 9.4 GHG 122.0 FGG 82.5 GGY * 1.3 GTW 464.5 GVW 240.0 PLANTS PeptoGrid KFY YKW RFH IWH 45.0 13.3 330.5 3.5 AGS VAA GAP...