Humans have undergone intense evolutionary selection to optimize their capacity to generate necessary quantities of long chain (LC-) polyunsaturated fatty acid (PUFA)-containing lipids. To better understand the impact of genetic variation within a locus of threegenes (,, and) on a diverse family ...
You are performing chemical tests on a sample of fatty acid. You find that you cannot hydrogenate the sample, leading you to suspect that it is: a. saturated b. monounsaturated c. polyunsaturated d. phospholipids e. nucleic acids Ethidium bromide is used...
Omega-(n)-3 polyunsaturated fatty acids (PUFAs), including docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are major components of neuronal memb... DW Luchtman,C Song - 《Neuropharmacology》 被引量: 249发表: 2013年 Biochemical and Nutritional Influences on Pain Inflammation may be co...
S. et al. Inhibition of translation initiation mediates the anticancer effect of the n-3 polyunsaturated fatty acid eicosapentaenoic acid. Cancer Res. 60, 2919–2925 (2000). CAS PubMed Google Scholar Dragnev, K. H., Freemantle, S. J., Spinella, M. J. & Dmitrovsky, E. Cyclin ...
Lipid metabolism is closely related to CRC, of which excess lipid derivates particularly the pro-inflammatory n-6 polyunsaturated fatty acids (PUFAs), could promote colorectal tumorigenesis.19 Indeed, here we observed the enrichment of multiple n-6 PUFAs in the plasma metabolome of CRC, such as...
specific volatile markers for breast cancer; in particular, the research- ers proposed that these compounds were produced because the mito- chondrial release of reactive oxygen species (ROS) created oxidative stress that resulted in lipid peroxidation of polyunsaturated fatty acids in the cell membrane...
There were no differences in liver saturated fatty acid (SFA), polyunsaturated fatty acid (PUFA), C16:0, C18:0, C18:2n6c, C18:3n6, C18:3n3, C20:0, C20:4n6, C22:0 between the PAD and CON groups. However, compared to the CON group, PAD decreased liver total fatty acid (TFA),...
Human hepatoblastoma cells (HepG2) were treated simultaneously with different types of FFAs (saturated, monounsaturated and polyunsaturated) and levels of TNF-α and the cytotoxic, metabolic and genetic responses were studied. Exposing the cells to saturated fatty acid (palmitate) was cytotoxic and th...
Targeted metabolomics reveals reduced levels of polyunsaturated choline plasmalogens and a smaller dimethylarginine/arginine ratio in the follicular fluid of patients with a diminished ovarian reserve. Hum. Reprod. 32, 2269–2278 (2017). Article PubMed CAS Google Scholar Revelli, A. et al. ...
traits showing significantly enriched terms are reported (FDR < 0.05). (a) GO terms; (b) KEGG-pathways. ID14:1: 14:1/(14:1+14:0); ID16:1: 16:1/(16:0+16:1); MUFA: monounsaturated fatty acids; PUFA: polyunsaturated fatty acids; SFA: saturated fatty acids; TFA:transfatty ...