A method to identify hadronic molecules in the particle spectrum is reviewed and the conditions for its applicability discussed. Special emphasis is put on the discussion of molecule candidates in the baryon spectrum.doi:10.1140/epja/i2007-10568-1C. Hanhart...
An aptamer-based SERS detection technique that directly monitors an aptamer-analyte capture event by generating spectroscopic information regarding the identity of the analyte that has been bound to the aptamer from a complex biological sample. A reproducible SERS spectrum is measured for an aptamer-ana...
a smooth muscle cell-like phenotype presumed to be highly secretory10and contractile11,12,13. Myofibroblasts are most often identified in vitro by the de novo assembly of alpha-smooth muscle actin (α-SMA) stress fibers14,15,16, although recent research has shown that α-...
Within the central metabolism category, the genesTPS2andTPS1were identified with high frequencies in both up and down-regulated clusters. These genes encode the primary enzymes involved in the synthesis of trehalose, a stress protectant molecule that plays a crucial role in the response to various ...
I think I understand the basics of interpreting an IR, but I don't really understand how to determine the structure from an NMR. What exactly do the peaks tell you, and what is a chemical shift? How can I tell how many carbons are in each molecule, and what other functional groups th...
Drug sensitivity analysis GSCALite incorporates information on over 750 small-molecule medications from the GDSC and CTRP databases101. To evaluate the sensitivity of the MCM4 gene and its interactions with other genes in relation to multiple anticancer drugs, GSCALite was used.Data...
Some autism spectrum disorders (ASD) likely arise as a result of abnormalities during early embryonic development of the brain. Studying human embryonic brain development directly is challenging, mainly due to ethical and practical constraints. However,
The need to control the activity and fidelity of CRISPR-associated nucleases has resulted in a demand for inhibitory anti-CRISPR molecules. The small-molecule inhibitor discovery platforms available at present are not generalizable to multiple nuclease classes, only target the initial step in the catal...
Next, the group wanted to know if blocking Th17 cells could lessenperiodontal disease. When the scientists genetically engineered mice to lack Th17 cells, or gave the animals a small-molecule drug that prevents Th17 cell development, they saw similar outcomes: reducedbone lossfrom periodontitis. RNA...