Answer to: Identify the molecule below according to its functional group. By signing up, you'll get thousands of step-by-step solutions to your...
For the molecule shown below, draw the most stable conformations and identify any non-bonding interactions. The Conformation The three-dimensional arrangement of C-atoms and H-atoms, which can be converted into each other by the rotation around the carbon-carbon single...
A unique, protective cell envelope contributes to the broad drug resistance of the nosocomial pathogen Acinetobacter baumannii. Here we use transposon insertion sequencing to identify A. baumannii mutants displaying altered susceptibility to a panel of d
The Affimer that binds to the SI/SII pocket actually mimics the current small molecule inhibitors that target the pocket as seen in a competitive NanoBRET assay, providing a proof-of-principle for using Affimer-target interfaces as pharmacophore templates. The Affimer that binds the SII region ...
Moreover, NA mutants obtained by such passaging were able to grow in cell cultures lacking exogenous sialidase activity, as well as in eggs and mice, as a result of compensatory mutations in the HA protein that reduce the molecule's affinity for sialic acid residues (Hughes et al., 2000)...
Besides, one of the terminal benzenes is located in a hydrophobic pocket, formed by Leu133, Val139, Phe130 and Leu202, whereas the other benzene terminal is located in a hydrophobic area that has been formed by the amino acids Trp115 and Tyr157, which stabilize the molecule. The terminal...
The blue bars below represent the protein fragments encoded by the cDNA inserts contained in the corresponding phosphatidylinositide-binding clone. The gene exon structure is shown in green. Because the gene exon structures are interrupted by nonprotein coding intronic sequences, they do not ...
This is because one mechanism by which compounds can act as carcinogens is by damaging the DNA in the nuclei of cells, that is by being genotoxic, and for genotoxic carcinogens one molecule could be sufficient to initiate or promote tumours, and therefore no level of exposure should be deemed...
The crystal structure of VEB-1 β-lactamase has not been described. Determining the three-dimensional (3D) structure of this molecule would assist in the discovery of more potent inhibitors, particularly in the application of structure-based virtual screening to identify lead compounds. To this end...
(Fig.2). NRT1 acts as both a low- and high-affinity nitrate transporter inArabidopsisdepending on it phosphorylation status [50]. Nitrate concentrations appear to be important because nitric oxide (NO) is an important signaling molecule in ABA-induced stomatal closure and the production of NO ...