A high throughput single-molecule method for identifying peptides and sequencing proteins based on nanopores could reduce costs and increase speeds of sequencing, allow the fabrication of portable home-diagnostic devices, and permit the characterization
Although under physiological conditions ZMP is present in the micromolar range (7), upon feeding of the riboside precursor AICAR, ZMP concentration can increase to milli molar levels (1), and, as a result, AICAR displayed cytotoxicity in yeast and mammalian cells (2), although the exact ...
present (i.e., on a molar basis it is more abundant than any other individual species in the composition), and preferably a substantially purified fraction is a composition wherein the object species comprises at least about 50 percent (on a molar basis) of all macromolecular species present....