What is the final result of the mitotic phase? Fill in the blank. "Zygote" is the term used to describe the ___. What are the phases of the cell cycle and how variable are their durations? What is the function of the spindle fibers during mitosis? What features of the structure ...
LCNEC and SCLC require upfront aggressive, multimodal treatment for most of the patients. Owing to these differences in clinical management and prognosis, the accurate diagnosis of these diseases is critical. However, there is still no consensus on the optimal approach for their...
or the obstruction of the reproductive tract, affects about 1% of all men and is prevalent in up to 10–15% of infertile males. Conventional semen analysis remains the gold standard for diagnosing and treating male infertility; however, advances in molecular biology and bioinformatics...
There are seven major phases in this work’s overall approach. The dataset for blood (PBMC) cells is obtained in the first step. This step aims to make sure that the samples are taken from COVID-19. The differentially expressed genes (DEGs) from each of the selected datasets were determin...
Heme metabolism, interferon-alpha, and interferon-gamma pathways were modulated in patients at both exacerbation and stable-state visits, but with the involvement of distinct sets of genes. An important gene community was enriched with G2M checkpoint, E2F targets, and mitotic spindle pathways during...
Gene ontology analysis for the Biological processes (GO-BP) of upregulated genes at 12-h time point revealed the enrichment of cell cycle-related processes such as chromosome segregation, mitotic nuclear division, and regulation of nuclear division, as well as the enrichment of antiviral innate imm...
In addition, FGF5 stimulates hypertrophic and partial cardiomyocytes to re-enter the mitotic phase of the cell cycle, which restores the function of hibernating myocardium following MI [53]. In contrast to the cardioprotective effects of FGF5, our MR results indicate that FGF5 is a risk factor ...
The strategy utilized here constitutes an interesting way to assess the fate of stem cell in culture based on in vitro readouts, by associating expression of specific stemness genes with the mitotic activity of the cells. This tool can be used as a preliminary screen for the effect of differe...
In normal hematopoiesis, megakaryocyte progenitors (MkPs) have a low proliferation rate, typically undergoing less than 8 cell divisions before mitotic arrest and the onset of polyploidization (Paulus et al., 2004), and megakaryoyctes are relatively rare cells in healthy bone marrow. The cellular...
(TMT)44. Briefly, we performed E2~dID according to Fig.1aand Fig.2c, using extracts of cells synchronized in anaphase. We chose mitotic extracts, where APC/C substrates are particularly well-characterized to aid our evaluation of the overall sensitivity and specificity of E2~dID. Notably, we...