Studies have indicated that the lipids in the tear film layer, which covers the outer portion of the eye, may be directly correlated with the existence of dry eye syndrome. By identifying and comparing the major, non-polar lipids in normal eye tears with a dry eye model,......
WRKY is another transcription factor family that regulates germination; senescence; development; biotic and abiotic stresses [60]; and the biosynthesis of three major classes of metabolites, namely, phenylpropanoids, alkaloids, and terpenes [61]. Similar to the AP2/ERFs, a WRKY family transcription ...
A molecular and functional understanding of major associations between insects and other organisms may result in the identification of useful genes and molecules for the development of new strategies to control harmful insects3,4, and also for biomedical and industrial applications through ...
African American-white differences in lipids, lipoproteins, and apolipoproteins, by educational attainment, among middle-aged adults: the atherosclerosis risk in communities study. Am J Epidemiol. 1998;148:750–60. Article CAS PubMed Google Scholar Matthews KA, Kelsey SF, Meilahn EN, Kuller LH,...
Bacterial interactions with the environment- and/or host largely depend on the bacterial glycome. The specificities of a bacterial glycome are largely determined by glycosyltransferases (GTs), the enzymes involved in transferring sugar moieties from an a
A major advantage of untargeted metabolomic analysis over targeted metabolic testing is the wide range of metabolites and classes of metabolites that may be assayed in a single biological sample. Similar metabolite coverage by targeted approaches would otherwise require multiple individual clinical tests, ...
Studies on the toxicity of saturated FFAs to other cells have suggested that increased ROS production and ceramide synthesis [20, 21] are the major mechanisms of palmitate-toxicity in those cells. Similarly, increased ceramide and ROS generation have been suggested to play important roles in the ...
high throughput techniques that allow simultaneous examination of changes in the genome (DNA), transcriptome (mRNA), proteome (proteins), lipidome (lipids), and other biochem- ical components in a biological sample with the goal of understanding the physiology or mechanisms of disease [76–78]. ...
(E2) and luteinizing hormone measurements. Ultrasonography was the major tool evaluating FD from Day 5 of stimulation until maturation. Once ≥1 follicle (s) achieved a diameter of 18 mm, we increased E2 levels to match the quantity of follicles. 10,000 IU human chorionic gonadotropin (HCG...
Macrophages play an essential role in the early immune response against Toxoplasma and are the cell type preferentially infected by the parasite in vivo. Interferon gamma (IFNγ) elicits a variety of anti-Toxoplasma activities in macrophages. Using a gen