Full size image Table 1 Diagnoses from genomic autopsy. All ACMG-classified likely pathogenic (LP) and pathogenic (P) variants identified in the cohort, including follow-up investigations to confirm causality of eight VUS and two GUS. AR, autosomal recessive; AD, autosomal dominant; XLR, X-lin...
Genes whose gRNAs were significantly enriched or depleted in the infected group (P value < 0.05 and |log2FC | ≥0.5) were labeled as red and green dots, respectively. The top ten enriched/depleted (pro-viral/anti-viral) genes based on MAGeCK scores were indicated. P values were...
Users can provide multiple values for a match type in a single line of configuration; that is, if the first value does not meet the match criteria, then the next value indicated in the match statement is considered for classification. Use the not key...
Holistic features describing each image were also considered. The Kruskal-Wallis H test was used to identify significantly different features. Multiple comparisons were done using the rank-based version of Tukey-Kramer test. The results indicated that there are local and global features which differ ...
Download: Download full-size image Fig. 2. Flow diagram illustrating the number of patients and visits present at each phase of cohort processing. *Note: The number of unique patients in the Manually-Reviewed Test Set (702) is smaller than the sum of the 2 preceding boxes (717) because th...
aAlteration matrices illustrating differences between the combinatorial weight functionW(M) introduced in Dendrix and the probabilistic scoreΦ(M) used in CoMEt. Both matrices contain 4 mutually exclusive alterations whose alteration frequencies are indicated inside each bar. The samples without alterations...
Whether immune checkpoint inhibition, alone or in combination, is able to achieve long-term responses in advanced and metastatic ccRCC, similar to the responses observed in malignant melanoma, will emerge in the future. First studies also indicated that a multi-peptide vaccine was beneficial in ...
6h). In addition, DLA experiment confirmed that overexpression of Sox2 (using pcDNA3.1(+)-Sox2) increased the activity of enhancer with the non-risk allele but the not non-risk allele of rs560789 (Fig. 6i). These results indicated that the risk allele of rs560789 could impair the ...
Portraits of Roman emperors are traditionally recognised by their unique coiffure patterns, a method that runs the risk of ignoring portraits that do not cohere to the standardised image of the emperor. This article investigates whether it is possible to recognise and distinguish emperors using the ...
The main advantage of image post-processing methods is that they can positively differentiate among all the flow regimes. Yet, the implementation of image post-processing method in the actual multiphase system is expensive, time consuming and difficult to use in the industry. Other techniques which...