Carboxyl group footprinting mass spectrometry and molecular dynamics identify key interactions in the HER2-HER3 receptor tyrosine kinase interface. J Biol Chem. 2013;288:25254-64.Collier TS, Diraviyam K, Monsey J, Shen W, Sept D, Bose R. Carboxyl group footprinting mass spectrometry and ...
Identify the amino acid given below: Amino Acids: Amino acids contain a carbon atom attached to a carboxyl group, an amino group, an alkyl group side chain, and hydrogen. The amino acids differ by the number of carbon atoms and functional groups in the side chain. ...
Amino Acids: Identifying an amino acid is very easy because we only need one portion of the overall structure. The portion we need to know to recognize the amino acid is the side chain or the R-group. We do not need the carboxyl group and the amino group because these two portions of...
athe neighboring layers are pillared through the O2 atoms from carboxyl group along the c-axis, leading to the formation of a 3D framework (Figure 6c 正在翻译,请等待...[translate] a通过制作抽认卡来学习英语是一个很好的方法 正在翻译,请等待...[translate] ...
IHC with D5F3 The clone D5F3 recognizes the carboxyl terminus of human ALK protein, and many studies have reported excellent per- formance of the clone D5F3. Mino-Kenudson et al38 showed a 100% sensitivity and 99% specificity of IHC with the D5F3 (1:100; Cell Signaling Technology,...
F-box proteins consist of two main functional domains: (i) F-box motif and (ii) a carboxyl-terminal domain. F-box motif is a protein–protein interaction domain that recruits F-box proteins to the SKP1-CULL1-F-box protein (SCF) E3 ligase complex through direct binding to the adaptor ...
[13] Low BC, Seow KT, Guy GR (2000) Evidence for a Novel Cdc42GAP Domain at the Carboxyl Terminus of BNIP-2. Journal of Biological Chemistry 275: 14415–14422. [14] Zhou YT, Soh UJK, Shang X, Guy GR, Low BC (2002) The BNIP-2 and Cdc42GAP Homology/Sec14p-like Domain of BN...
A, the carboxyl-terminal PASTA4 repeat in complex with Zn2+ (gray spheres). Zn2+-bound residues are highlighted. The key structural features include ψ-loop (β1β2β3) nestling the α1 helix and a β′/β″ brace close to the N terminus of the domain. B, PASTA3 domain of PknB...
Biochemical and growth inhibition studies of methotrexate and aminopterin analogues containing a tetrazole ring in place of the gamma-carboxyl group. The biological activities of novel analogues of methotrexate (MTX) and aminopterin (AMT) in which the gamma-carboxyl was replaced by a 1H-tetrazol-5...
This protein enhances lysophosphatidic acid (LPA) -induced cell migration by directly binding to the carboxyl-terminal tail of the LPA2 receptor through its LIM domains [51]. Moreover, TRIP6 might enhance cell migration by binding to PDZ domain of MAGI-1b/PTEN destabilizing membrane β-catenin...