The molecular features of PCC components were initially revealed, including low expression of caudin-3, -4 and -7, high expression of IGFBP7, and expression of PD-L1. These features may partially explain the strong tumor heterogeneities of GC and aid pathologists in distinguishing PCC components...
This workflow is common when conducting data movement orchestration. Synapse Analytics pipelines makes it easy to define data movement and transformation steps, and encapsulates these steps into a repeatable process that you can maintain and monitor within your modern data...
This workflow is common when conducting data movement orchestration. Synapse Analytics pipelines makes it easy to define data movement and transformation steps, and encapsulates these steps into a repeatable process that you can maintain and monitor within your modern data wa...
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Ischemic heart disease is one of the leading causes of mortality worldwide, and thus calls for development of more effective therapeutic strategies. This study aimed to identify potential therapeutic targets for coronary heart disease (CHD) and myocardia
The results of single-cell analysis showed that responseScore was closely related to the functional state of natural killer cells. Compared with the PCDH-NC group, cell migration and proliferation were significantly inhibited while cell apoptosis increased in the PCDH-PSMB9 group. Conclusion The GNNs...
Molecular Autism (2020) 11:58 Page 2 of 14 neuronal physiological maintenance; and synaptic pro- cesses. The convergence of many ASD-risk genes on common molecular pathways may help explain how a genetically heterogeneous population of individuals ex- hibit similar symptoms. One such point of ...
Lung adenocarcinoma (LUAD) is the predominant histological subtype of lung cancer and the leading cause of cancer-related mortality. Identifying effective drug targets is crucial for advancing LUAD treatment strategies. This study employed proteome-wide
. Associations of DNA methylation with kidney function, such as CpGs atJAZF1,PELI1andCHD2were validated in kidney tissue. Methylation atPHRF1,LDB2,CSRNP1andIRF5indicated causal effects on kidney function. Enrichment analyses revealed pathways related to hemostasis and blood cell migration for ...
Foraging is a key driver of animal movement patterns, with specific challenges for predators which must search for mobile prey. These patterns are increasingly impacted by global changes, principally in land use and climate. Understanding the degree of f