Cancer cell lines exhibit variability in splicing isoforms of the same gene and in their dependency on specific genes following knockdown (KD). When shRNA KD screens target the entire pool of isoforms of a gene, diverse responses in different cell lines may result from variations in the inclusio...
Functional studies of long noncoding RNAs (lncRNAs) have been hindered by the lack of methods to assess their evolution. Here we present lncRNA Homology Explorer (lncHOME), a computational pipeline that identifies a unique class of long noncoding RNAs (lncRNAs) with conserved genomic locations an...
The pipeline produces a set of three types of putative regulatory motifs involving coding genes, intronic miRNAs, and transcription factors. We used this pipeline to analyze the results of a set of expression experiments on a melanoma cell line that showed an over expression of miR-214 along ...
Such projects vary in terms of size, contributors, domains, ecosystems, and coding style guidelines (or comment guidelines). As not all classes contain a class comment, we identified the classes having class comments for each project. Afterward, we extracted a statistically significant sample of ...
The HHS asked if participants had experienced 13 different types of VAW in the public sphereFootnote14and where these incidents took place. If a participant had experiences of violence, and remembered the location, the location was registered as a polygon or a line over a map in a tabletFoot...
For qualitative data, utilizecontent analysisand thematic coding to uncover deeper insights from interviews and open-ended responses. Cross-reference these findings to build a thorough picture of your audience’s behaviors and preferences. To measurecustomer satisfactionand strengthen customer relationships,...
In one embodiment, the mutant cell has at least 2, 3, 5, 7, or 10, or more, e.g., 12, 15 or 20, fold lower levels of one or more different types of sialic acid relative to the corresponding wild-type cell. [0009] To isolate a mutant cell of the invention, e.g., a ...
Gene rsph17025_3695 encodes a predicted nuclease and overlaps with the last 4 nt of the RsAgo coding sequence. PAZ, MID, and PIWI are conserved domains shared by all Argonautes, while N (N-terminal), L1 (linker 1), and L2 (linker 2) are not conserved. (B) Purified RsAgo is ...
The base is cytosine. It is found in both DNA and RNA. The given base is a pyrimidine as it contains only one ring. Based on the types of atoms...Become a member and unlock all Study Answers Start today. Try it now Create an account Ask a question Our experts can ...
of 1000 Genome Project phase 3 (“Methods”). We prioritized 406 unique genes from 20 PSC susceptibility loci reported in Supplementary Data5that functionally mapped and annotated using MTAG-identified GWAS, of which 109 genes were identified by position mapping of deleterious coding variants with ...