A process for identifying genes coding for cellular constituents involved in regulating angiogenesis including culturing endothelial cells on an extracellular matrix protein according to at least four different types of conditions: a reference condition, an angiogenesis promoting condition, an angiogenesis inhi...
Such projects vary in terms of size, contributors, domains, ecosystems, and coding style guidelines (or comment guidelines). As not all classes contain a class comment, we identified the classes having class comments for each project. Afterward, we extracted a statistically significant sample of ...
FindIT2 supports a complete framework for annotating ChIP-seq/ATAC-seq peaks, identifying TF targets by the combination of ChIP-seq and RNA-seq datasets, and inferring influential TFs based on different types of data input. The mmAnno module accepts the bed or bed-like format file like ...
The pipeline produces a set of three types of putative regulatory motifs involving coding genes, intronic miRNAs, and transcription factors. We used this pipeline to analyze the results of a set of expression experiments on a melanoma cell line that showed an over expression of miR-214 along ...
of 1000 Genome Project phase 3 (“Methods”). We prioritized 406 unique genes from 20 PSC susceptibility loci reported in Supplementary Data5that functionally mapped and annotated using MTAG-identified GWAS, of which 109 genes were identified by position mapping of deleterious coding variants with ...
Of these, the variant was non-coding in 13 JT and 7 QRS loci. Association with gene expression levels in cardiac tissue Using data from the Genotype-Tissue Expression (GTEx) project33, we identified 39 (22.2%) multi-ancestry QT loci where a variant was a cis-eQTL in left ventricle (LV...
scale metabolic models in different conditions (minimal and rich mediums) for the overproduction of a number of desired metabolites. FastKnock efficiently prunes the search space to less than 0.2% for quadruple- and 0.02% for quintuple-reaction knockouts. Compared to the classic approaches such as...
The given base is a pyrimidine as it contains only one ring. Based on the types of atoms... Learn more about this topic: Nucleic Acid | Function, Structure & Importance from Chapter 4/ Lesson 5 98K Why are nucleic acids important? In this lesson, understand the nucleic acid...
Gene rsph17025_3695 encodes a predicted nuclease and overlaps with the last 4 nt of the RsAgo coding sequence. PAZ, MID, and PIWI are conserved domains shared by all Argonautes, while N (N-terminal), L1 (linker 1), and L2 (linker 2) are not conserved. (B) Purified RsAgo is ...
Functional studies of long noncoding RNAs (lncRNAs) have been hindered by the lack of methods to assess their evolution. Here we present lncRNA Homology Explorer (lncHOME), a computational pipeline that identifies a unique class of long noncoding RNAs (lncRNAs) with conserved genomic locations an...