Advanced bone phenotyping assays Deciding which KOs showing potential skeletal pheno- types in the primary HTS merited advancement to second- ary screening involved both statistical and judgmental considerations. Given that multiple parameters were measured from a small numbers of mice, strict statistical...
Deciding which KOs showing potential skeletal phenotypes in the primary HTS merited advancement to secondary screening involved both statistical and judgmental considerations. Given that multiple parameters were measured from a small numbers of mice, strict statistical tests were not employed. Knowing the ...
Vaccine failures are due to expression of variants of the major surface proteins MSP2 and MSP3. A. marginale creates a wide array of antigenic variants by substitution of whole or partial pseudogene cassettes into a single genomic expression site by segmental gene conversion [8], [9], [10],...
Deciding which KOs showing potential skeletal phenotypes in the primary HTS merited advancement to secondary screening involved both statistical and judgmental considerations. Given that multiple parameters were measured from a small numbers of mice, strict statistical tests were not employed. Knowing the ...
DIPA-family coiled-coils bind conserved isoform-specific head domain of p120-catenin family: potential roles in hydrocephalus and heterotopia Mol. Biol. Cell, 25 (17) (2014), pp. 2592-2603 View in ScopusGoogle Scholar Marshak et al., 1992 D.R. Marshak, S.A. Pesce, L.C. Stanley, W...
Fig. 7: Investigation of potential germline stem cells in the adult human ovarian cortex. Data sets of unsorted and sorted ovarian cortex cells were used individually for integration with scRNA-seq data set of human fetal tissue cells22. a UMAP plot showing sample origin of fetal (black) and...
To identify potential target labels, we screened 410 genes encoding cell-surface and secreted proteins, searching for those whose overexpression on all muscle fibers causes motor axons to make targeting errors. Thirty such genes were identified, and a number of these were members of a large gene ...
By this means, these medicinal plant -derived compounds show potential as adjuvant therapies for intracellular bacteria resuscitation. Keywords: bacterial persistence; dormancy; glutathione; antibacterial agent; adjuvant therapy; natural product 1. Introduction In the course of evolution, bacteria have ...
To further assess the potential of CL9406 scaffold compounds as new anti-Giardia compound leads, the in vitro activity of SN00797640 was further investigated. This included re-purchasing the compound and examining activity against the assemblage A parasite line BRIS/87/HEPU/713, the metronidazole re...
By exploiting a very small part of these data, we succeeded in developing a method whose applications are: (i) the early identification of putative off-targets and the hasty forecast of cross-reactions, but also (ii) the identification of large sets of CDRs-distinct of potential binders for...