It centers on Poirot investigating a murder during a luxurious cruise on the Nile River that he just happens to be on. 故事的主要内容是在尼罗河上的一次豪华巡航中,波洛恰好在现场,并调查这起谋杀案。 But just as he identifies a motley collection of would-be killers, several of the suspects ...
These findings demonstrated that genes in the LPCAT family might be used as cancer immunotherapy and prognosis-related biomarkers. Specifically, LPCAT4 could be a treatment target of HCC.Yaoyong LuHongfeng LiangXiaoyin LiHaiwen ChenChangfu Yang...
AThe proportion of tumors harboring each driver mutation in localized prostate cancer or mCRPC (‘Observed Δ Proportion’), as described. Dot size indicates −log10q-value; dot color indicates driver mutation type. Specific genes of interest are labeled.BComparison of driver gene mutation prevalen...
To test a functional role for these proteins, we generated dominant negative forms of these proteins where possible, and compared the amplitude plots of the CaaX marker as a measure of the extent of perturbation (Fig. 6l, m). We found a marked reduction in amplitude with expression of some...
A solution of LB* + 1% (v/v) DMSO was used as a negative control. Test compounds were distributed amongst one flat-bottom, 384-well microplate (cat no. 3860; Corning, Corning, NY, USA). Eighty xL3s of H. contortus in 20 µl of LB* were added to each well to give a ...
This isoform possesses specific regulatory properties, so this finding indicates it may be involved in metabolic remodeling and also serve as a novel candidate biomarker. Levels of translation factor eEF1 also increased during TAC, likely contributing to faster cell mass accumulation. Interestingly those...
F. Search for novel targets of the P II signal transduction protein in Bacteria identifies the BCCP component of acetyl- CoA carboxylase as a P II ... TE Rodrigues,ECM Gerhardt,MA Oliveira,... - 《Molecular Microbiology》 被引量: 39发表: 2013年 Over-expression of sterol-regulatory-element...
However, the analysis of the large transcriptome data available through CATdb [16] may provide the first insights as to their functions. Inference on functions for unknown genes by such a compendium approach has already been successfully reported on yeast [23]. The fact that Eugene Markov model...
Further analysis shed light on the robust role of CLEC1B in the immune response, which is involved in the biological processes of immune cell activation, differentiation, and proliferation. The KEGG analysis of CLEC1B revealed a marked association with immune-related pathways such as the “cytokin...
Seven gRNAs that do not target the mouse genome were also included as negative controls. These 14675 gRNAs were synthesized as an oligonucleotide pool, cloned into the CM specific CASAAV vector, and packaged into AAV9 (see “Methods”). To introduce a positive control, a small amount of the...