L. Sir2 mediates longevity in the fly through a pathway related to calorie restriction. Proc. Natl Acad. Sci. USA 101, 15998–16003 (2004). Article CAS PubMed PubMed Central Google Scholar Hashimoto, T., Horikawa, M., Nomura, T. & Sakamoto, K. Nicotinamide adenine dinucleotide extends...
A major part of the transcriptome complexity is attributed to multiple types of DNA or RNA fusion events, which take place within a gene such as alternative splicing or between different genes such as DNA rearrangement and trans-splicing. In the present
lzexpression in the female genital disc was activated through the lz-DBS1 and the lz-DBS2. Abstract Normal sexual differentiation in the genital organs is essential for the animal species that use sexual reproduction. Although it is known thatdoublesex(dsx) is required for the sexual development...
In this study, we sought to assess the status of O. volvulus transmission in the study communities and explore the the black fly species composition sustaining transmission of onchocerciasis in the study areas. Considering that the disease is endemic in nine of the ten regions of the country dur...
The ability to inexpensively describe taxonomic diversity is critical in this era of rapid climate and biodiversity changes. The recent genome-skimming approach extends current barcoding practices beyond short markers by applying low-pass sequencing and
TRAF6 and the three C-terminal lysine sites on IRF7 are required for its ubiquitination-mediated activation by the tumor necrosis factor receptor family member latent membrane protein 1 Mol. Cell Biol., 28 (2008), pp. 6536-6546, 10.1128/MCB.00785-08 View in ScopusGoogle Scholar 69 Y. Yang...
While much of the past work has applied adaptive characterization to fixed samples with unchanging properties, we show in this paper that the use of in-line ML analysis can also enable improved monitoring of dynamic processes where rapid measurements are required to capture transient states. For ...
In order to carry out a ROC curve analysis, a dataset with known positive events is required. We used a set of 75 mass spectrometry traces from a simulated protein spectra dataset29 and found that our algorithms slightly outperforms other CWT techniques. Details are provided in the ...
The Exuperantia (Exu) protein in our insect-specific set is the earliest factor known to be required for the localization of bicoid mRNA to the anterior pole of the Drosophila oocyte. Exu is highly enriched in the sponge bodies; mutation of exu in Drosophila may result in defection of ...
inhibitory serpin-fold to evolve from an active inhibitor than the reverse; a single substitution within the conserved hinge-region motif can inactivate the inhibitory mechanism [4]; while a series of changes in a non-inhibitory serpin-fold would be required to generate the hinge-region consensus...