Nutrition Identification of Transcription Factors involved in Obesity SACKLER SCHOOL OF GRADUATE BIOMEDICAL SCIENCES (TUFTS UNIVERSITY) Jose M. Ordovas LaneJacqueline MObesity is a leading cause of preventable death in the United States. With the prevalence of obesity >30% in the United States, to ...
Using yeast one-hybrid and dual-luciferase assays, we demonstrated that the transcription factors RrHY5H and RrZIP9 bind to the promoter of RrGGP to promote its expression. RrZIP6 and RrWRKY4 bind to the LTR in the RrGalUR promoter to promote its expression. Our results reveal a ...
as a part of the PurR regulon (Fig.1)11. Genes encoding the purine biosynthetic pathway and the transporters (ghxP,xanP) were found to be repressed in the presence of exogenous adenine, whereas two genes were upregulated in the presence...
Transposase-Accessible Chromatin followed by sequencing (ATAC-seq) is a simple protocol for detection of open chromatin. Computational footprinting, the search for regions with depletion of cleavage events due to transcription factor binding, is poorly understood for ATAC-seq. We propose the first foot...
Brown planthopper (BPH), Nilaparvata lugens Stål, is one of the most destructive insect pests of rice. The molecular responses of plants to sucking insects resemble responses to pathogen infection. However, the molecular mechanism of BPH-resistance in rice remains unclear. Transcription factors (TF...
The problem of identifying binding sites for transcription factors as such in experimentally yet unaccessed or unaccessible sequence domains is an interesting task for both biologically and statistically inclined research and several methods have been proposed to solve this riddle, some of them purely in...
This study first investigated global gene expression profiles at different developmental stages of flowering in A. amurensis by RNA-seq transcriptome and iTRAQ proteomics. Finally, 123 transcription factors (TFs) were detected in both the transcriptome and the proteome. Of these, 66 TFs belonging to...
Transient activation of Src oncoprotein in non-transformed, breast epithelial cells can initiate an epigenetic switch to the stably transformed state via a positive feedback loop that involves the inflammatory transcription factors STAT3 and NF-κB. Here
A complex genetic regulatory network orchestrates the underlying biochemical modifications, but very few transcription factors specific to this programme have been identified to date. Here, we...会议名称: Annual Congress of the 会议时间: 2009/03/01 ...
Bubble area size: number of genes in the target gene set that belong to a pathway. Bubble color: enriched in terms of significance according to the p-value Full size image Identification of transcription factors related to fertility restoration The regulation of plant gene expression comprises a ...