By contrast, fish add nephrons throughout their lifespan and regenerate nephrons de novo after injury, providing a model for understanding how mammalian renal regeneration may be therapeutically activated. Here we trace the source of new nephrons in the adult zebrafish to small cellular aggregates...
The distal nephron of the kidney plays a key role in the regulation of renal calcium excretion. Although calcium filtered at the glomerulus is reabsorbed along the whole length of the nephron, active, and by inference transcellular, tran... Yu,Alan S L - 《Kidney International》 被引量: 10...
amplified, and cDNA quality was evaluated using an Agilent 4200 instrument. Then, according to the instructions of the manufacturer, the scRNA-seq library was prepared using the single-cell 3′ library gel bead kit V2. Finally, sequencing was performed on an Illumina NovaSeq 6000 at a depth o...
Nephron segmentLectin-binding patterns in normal canine kidneys were histochemically investigated using eight lectins. WGA, ConA, and RCA-I showed positive signals in glomerular capillary walls, with signals for RCA-I being detected heterogeneously. In tubular segments, signals for WGA, s-WGA, ConA...
On the basis of each enzyme activity, it was possible to recognize different categories of tubules in the mouse nephron. In fact, both enzymes were heterogeneously distributed along the proximal tubule, but in opposite gradients. The various staining intensities probably corresponded to proximal ...
However, the proposed scheme has advantages over the preexisting scheme, such as: the proposed method can be used to identify both CKD stage and the nephron loss in different kidney regions, and it identifies CKD stage without using a classifier. Therefore, the proposed patter...
Identification of Molecular Mechanisms Regulating Mammalian Nephrogenesis Duration and Nephron Endowmentdoi:10.1681/ASN.20213210S153cAlison E. JarmasCincinnati Children's Hospital Medical Center, Cincinnati, OH;Praneet ChaturvediCincinnati Children's Hospital Medical Center, Cincinnati, OH;Raphael Kopan...
Nephron segmentsConflicting theories on the existence of several renal arginase isoenzymes remain in debate. Because the activity of arginase is high in two embryologically different nephron segments of the Meriones shawi kidney, namely the cortical (CPST) and medullary (OSPST) proximal straight ...
Electrophysiological identification of ??- and ??-intercalated cells and their distribution along the rabbit distal nephron segmentsdoi:10.1172/JCI114913Shigeaki MutoK YasoshimaKoji YoshitomiYasushi Asano
Identification of the site of glucocorticoid action on neutral amino acid transport in superficial nephrons of rat kidney. Amino Acids 2000; 18(3): 279-88.Schwertfeger M, Roskos M, Fleck C (2000) Identification of the site of glucocorticoid action on neutral amino acid transport in superficial...