The paper deals with boundary optimal control methods for partial differential equation (PDE) problems with both target and control variables on specified parts of the boundary of the problem domain. Besides the
Vabishchevich P.N., Vasil'ev V.I., Vasil'eva M.V., Computational identification of the right-hand side of a parabolic equation, Comput. Math. and Math. Phys., 2015, 55 (6), 1015-1021Vabishchevicha, P.N., Vasil´ev, V.I., Vasil´eva, M.V.: Computational identification of...
(1972) "A Computational Approach to the Combined Problem of Optimization and Parameter Identification," Automatica, Vol. 8, No. 3, pp. 337-347.Haimes, Y. Y., and D. A. Wismer, “A Computational Approach to the Combined Problem of Optimization and Parameter Identification,” Automatica , ...
These datasets encompass a wide range of behaviors, presenting difficult and unique computational challenges to pose estimation and tracking (Fig. 1a and Extended Data Fig. 2). The three mice frequently contact and occlude one another. The parenting dataset contained a single adult mouse with ...
Overall, to solve the problem of the integration of large microbiota datasets, more reliable approaches are urgently needed. Fig. 1: Batch effects and challenges in meta-analysis of the gut microbiota. a, Common challenges in the integration of multiple datasets. b, Principal coordinates analysis ...
RNA splicing is an important driver of heterogeneity in single cells through the expression of alternative transcripts and as a determinant of transcriptional kinetics. However, the intrinsic coverage limitations of scRNA-seq technologies make it challen
(e.g., a reference atlas). scrna-seq classification methods are relatively new compared to the plethora of methods addressing different computational aspects of single-cell analysis (such as normalization, clustering, and trajectory inference). however, the number of classification methods is rapidly ...
Mass spectrometry has become the analytical method of choice in metabolomics research. The identification of unknown compounds is the main bottleneck. In addition to the precursor mass, tandem MS spectra carry informative fragment peaks, but the coverage
combined with the introduction of particular instruments, allow to avoid the use ofsingular values decompositionto recursively estimate the signal subspace in a noisy framework. A particular attention is paid to the computational load of the developed methods. The performances of these algorithms are hi...
Topologically associating domains (TADs) are critical structural units in three-dimensional genome organization of mammalian genome. Dynamic reorganizations of TADs between health and disease states are associated with essential genome functions. However, computational methods for identifying reorganized TADs ar...