TRPM3 is a non-selective cation channel that is activated by neural steroids such as pregnenolone sulfate, nifedipine, and clotrimazole. Despite the number of TRPM3 variants, few reports have described functional analyses of these different TRPM3 types. Here we identified a new TRPM variant from...
Nature Communications volume 12, Article number: 5596 (2021) Cite this article 27k Accesses 20 Altmetric Metrics details Abstract Contact activation refers to the process of surface-induced activation of factor XII (FXII), which initiates blood coagulation and is captured by the activated partial ...
The number of PEBP family genes in moso bamboo is less than rice (19)9, maize (25)46 and poplar (9)47, and similar as Arabidopsis (6)15,21. The numbers of PEBP family members are different in various species. But, generally, the numbers of PEBP family members in monocots are 3–4...
The sequence alignment between Lbp23A (Protein ID: XP_001568545.1; GenBank accession number: LbrM.34.4450), Lbp23B (Pro- tein ID: XP_001564309.1; GenBank accession number: LbrM.20.0220) and hp23 was analyzed using CLUSTALW2 [44]. Our searches also revealed two p23 proteins in two other ...
The semaphorin family contains a large number of phylogenetically conserved proteins and includes several members that have been shown to function in repul... Alex L Kolodkin and Dorothy V Levengood and Erica G Rowe and Yu-Tzu Tai and Roman J Giger and David D Ginty - 《Cell》 被引量: ...
Several drugs that target a limited number of viral proteins are in preclinical and clinical development. Therapies that target viral proteins may result in varying pan-genotype efficacies due to the high degree of HCV sequence variation. The search for anti-viral therapies that target host proteins...
Expression of a number of genes during stationary phase In Escherichia coli is controlled by the alternative sigma factor σ 8 (KatF). Promoters recognized by σ 8 do not present a well-defined consensus sequence In their -10 and - 35 re... UM Espinosa,T Antonio - 《Nucleic Acids Researc...
The number of rFcε molecules bound per cell was calculated on the basis that GST•ε-(326-547) and GST•ε-(340-547) are dimers, while GST•ε-(226-354) is a monomer. Nonspecific binding was determined using a 50-100-fold molar excess of nonlabeled hIgE over 125I-hIgE, and ...
BMC Nephrology volume 16, Article number: 92 (2015) Cite this article 3271 Accesses Metrics details Abstract Background Familial hypomagnesemia with hypercalciuria and nephrocalcinosis is a rare autosomal recessive renal disease characterized by tubular disorders at the thick ascending limb of Henle’s ...
4b). The large number of false positives is mainly caused by metabolites that have similar dynamics. The same problem was previously reported for a multi-omics analysis of yeast metabolism, which searched for correlations between metabolites and fluxes27. In this study, correlations between ...