related to pancreatic acinar cells (GP2) and insulin secretion (GLP1R). Transethnic comparisons of the molecular pathways identified from the GWAS results highlight both ethnically shared and heterogeneous effects of a series of pathways on type 2 diabetes (for example, monogenic diabetes and beta ...
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GPRuler, an open-source computational framework to automate the reconstruction process of Gene-Protein-Reaction (GPR) rules within metabolic networks of a given organism based on the corresponding list of genes involved in catalysis of each metabolic rea
In the pre-image step, we assume the MFs of the TMS derivatives of compounds corresponding to the GC-EI-MS spectra from the test dataset to be known: This is certainly true if the GC-EI-MS spectra are generated for testing purposes, as in our case, but note that the MF corresponding ...
Prebiotics are defined as non-digestible dietary components that promote the growth of beneficial gut microorganisms. In many cases, however, this capability is not systematically evaluated. Here, we develop a methodology for determining prebiotic-respon
Prediction of new drug-target interactions is critically important as it can lead the researchers to find new uses for old drugs and to disclose their therapeutic profiles or side effects. However, experimental prediction of drug-target interactions is expensive and time-consuming. As a result, com...
Animals were evaluated for the excess heterozygosity, to check for possible cross-contamination among samples. To test for differences in the genetic background of the animals, a multi-dimensional scaling (MDS) plot was constructed using PLINK [16] and the R statistical environment [17]. Most ...
International Journal of Molecular Sciences Article Identification of Reference Genes for RT-qPCR Data Normalization in Cannabis sativa Stem Tissues Lauralie Mangeot-Peter 1, Sylvain Legay 1, Jean-Francois Hausman 1, Sergio Esposito 2 and Gea Guerriero 1,* 1 Environmental Research and Innovation (...
Numerous quick detection techniques for pesticide residues have been created in such situations, making it simple, quick, and accurate to check pesticide residues. Some sensors, such as electrochemical and optical methods, can measure pesticides with adequate accuracy and over the proper time. The ...
viruses Article Epitope Identification and Application for Diagnosis of Duck Tembusu Virus Infections in Ducks Chenxi Li 1,†, Junyan Liu 2,†, Wulin Shaozhou 1, Xiaofei Bai 1, Qingshan Zhang 1, Ronghong Hua 1, Jyung-Hurng Liu 3,*, Ming Liu 1 and Yun Zhang 1,* 1 State Key ...