脑室内注射(intra-cerebroventricular injection,ICV)将药物直接注入脑室内。慢性实验须先将套管埋入脑内,管端距侧脑室壁约1mm,并固定于颅骨上,实验时将注射管通过套管置入侧脑室,注射微量药物。 武汉市第六医院门诊楼10楼
Hunterase ICV注射液15mg是世界上第一种也是唯一一种治疗粘多糖病II型病中枢神经系统症状的药物。 参考来源:Announcing Marketing Approval for Hunterase ICV Injection 15 mg, the World’s First Enzyme Replacement Therapy for Mucopolysaccharidosis Type II (Hunter Syndrome) Administered by ICV Injection...
Central (ICV) leptin injection increases bone formation, bone mineral density, muscle mass, serum IGF-1, and the expression of osteogenic genes in leptin-deficient ob/ob mice. J Bone Miner Res. 2011; 26 :1710–1720. doi: 10.1002/jbmr.406. [ Cross Ref ]...
Intracerebroventricular injection (ICV) of NMU induced the expression of Fos protein in the SCN cells and caused a phase-dependent phase shift of the ... K Nakahara,R Hanada,N Murakami,... - 《Biochemical & Biophysical Research Communications》 被引量: 157发表: 2004年 A novel simultaneous ...
The objective of present study was to determine the effects of ICV injection of adrenomedullin and its interaction with NPY and CCK receptors on food intake regulation. In experiment 1, chickens received ICV injection of saline and adrenomedullin (1, 2, and 3 nmol). In experiment 2, birds ...
ICV injection of OKA (200 ng) produced memory impairment as evidenced by no significant decrease in latency time to reach the hidden platform in water maze test. It produced increase in malondialdehyde (MDA), nitrite level, reactive oxygen species (ROS) generation, mitochondrial calcium ion [Ca2...
21days following ICV-STZ injection, rats treated with NAR had better learning and memory performance in the Morris water maze test compared with rats treated with saline. We demonstrated that NAR increased the mRNA expression of INS and INSR in cerebral cortex and hippocampus. In addition, NAR ...
AIM To study the effect oficvnocistatin ( 10~17 ) on nociceptin in antagonizing morphine analgesia in mice. 目的观察痛稳素碳末端八肽在小鼠脑内对孤 啡 肽对抗吗啡的镇痛作用的影响. 互联网 Icvinjection of NOS inhibitor methyl ester ( L - NAME ) also inhibited all of the VP - secreting ne...
Behavioral and biochemical effects of an ICV injection of streptozotocin in old Lewis rats 来自 Semantic Scholar 喜欢 0 阅读量: 18 作者:Arjan,Blokland,and,Jellemer,Jolles 摘要: Intacerebroventricularly (ICV) injected streptozotocin (STREP) decreases central glucose metabolism and energy metabolism, ...
Intracerebroventricular injection of CCK reduces operant sugar intake in pigs. Pigs have a strong appetite for sugar solutions and readily learn to perform operant responses (pressing a panel with their snouts) to obtain glucose solut... B.A. Baldwin,S Sukhchai - 《Physiology & Behavior》 被...