An alternative to combination ICS/albuterol reliever treatment is the use of separate ICS and SABA inhalers at the same time as reliever therapy. There is an evidence base for the efficacy and safety of this approach in both children and adults; however, there is a major practical limitation ...
forced expiratory volume in 1 s; FeNO: fraction of exhaled nitric oxide; GERD: gastro-esophageal reflux disease; ICS: inhaled corticosteroids; IQR: interquartile range; IL: interleukin; IgE: immunoglobulin E; LABA: long-acting beta-agonist; SABA: short-acting beta- agonist; YKL-40: human ...