To evaluate this concept prospectively, we predefined a sub-study of the EUropean Comparative Effectiveness Research to Assess the Use of Primary ProphylacTic Implantable Cardioverter Defibrillators (EU-CERT-ICD)[8]. The sub-study...
In this seminal study, a substantial proportion of patients with LVEF≤35%, and thus eligible for primary ICD implantation, had an elevated NRR [7]. This made it reasonable to hypothesize that in contrast to ICD-recipients with lower NRR, primary ICD prophylaxis would be less effective in ...
Elevated KIM‐1 showed no significant differences (each P = n.s.). In multivariate cox regression analysis, NAG as well as NT‐proBNP were both independent predictors for adequate ICD shock therapies as well as the combined endpoint, beside ejection fraction <35% (each P <.05). Diabetes, ...