为了检测血管细胞粘附分子 -1(VCAM-1)、内皮细胞-白细胞粘附分子 -1(E-selectin)和细胞间粘附分子 -1(ICAM-1)作为动脉粥样硬化分子标志物和冠心病发病预测因子的能力,我们研究了204例冠心病发病患者、272例颈动脉粥样硬化(CAA)患者和316例来自大型双种族社区动脉粥样硬化风险(ARIC)研究的对照组。 冠心病患者血清 V...
1.细胞粘附分子E.selectin、ICAM-1、VCAM-1在B细胞和浆细胞持续表达 免疫组织化学和原位杂交方法显示,T细胞缺陷裸鼠的脾细胞在没有细 胞因子刺激的情况下,也表达E.selectin蛋白及mRNA,而T细胞和B细胞 共同缺陷的SCID小鼠却不表达E.selectin。进一步免疫电镜证实该种细胞是 ...
可溶性E一选择素 SeIectin 选择素 IntegriII 整合素 IgSF 免疫球蛋白超家族 Cadherin 钙粘附素 LFA.1 淋巴细胞功能相关抗原-1 PAF 血小板活性因子 LFA 淋巴细胞功能相关抗原 VCAM一1 血管细胞粘附分子一1 SPSS 社会科学统计软件包 6 结直肠癌可溶性ICAM-1和E-selectin的检测和意义 ...
Soluble levels of E-selectin, ICAM-1, and VCAM-1 were significantly elevated in patients with Stage 4 disease compared with controls. (E-selectin 88.6 (47.9) versus 51.4 (18.4) ng/ml; 展开 关键词: Adhesion molecules E-selectin ICAM-1 VCAM-1 Prognosis ...
目的研究动脉粥样硬化主动脉管壁内ICAM-1、VCAM-1及E-selectin的表达情况,探讨这些分子与动脉粥样硬化发生及彼此之间可能的关系。方法收集尸检证实主动脉粥样硬化的标本,常规石蜡切片,特异性免疫组化染色,观察ICAM-1、VCAM-1和E-selectin阳性反应细胞的数量及分布,测定阳性产物表达的平均灰度值。结果ICAM-1、VCAM-1、...
细胞间黏附分子-1(ICAM-1) 1. The level of adhesion molecules,including intercellular adhesion molecule-1(ICAM-1),vascular cell adhesion molecule-1(VCAM-1) and E-selectin,were measured before and after treatment. 方法将66例脑出血患者分为常规治疗组33例和HBO治疗组33例,分别于治疗前后测定血清细胞间...
In conclusion, there was a significant increase in circulating levels of ICAM-1, VCAM-1 and E-selectin in NAFLD compared to healthy control subjects and it may be used to comprehensively using the ability of circulating VCAM-1, E-selectin and ICAM-1 to predict fatty liver disease and ...
Gearing JH, Hemingway I, Pigott R, Hughes J, Rees AJ, Cashmann SJ: Soluble forms of vascular adhesion molecules, E-selectin, ICAM-1 and VCAM-1: Pathological significance. Ann NY Acad Sci 667:324-331, 1992 Google Scholar Pober JS, Gimbrome MA, Lapierre LA, Mendrick DL, Fiers W, Ro...
Soluble forms of the adhesion molecules ICAM-1, VCAM-1 and E-selectin have been detected in supernatants from cytokine activated cultured endothelial cells... R Pigott,LP Dillon,IH Hemingway,... - 《Biochem Biophys Res Commun》 被引量: 1443发表: 1992年 Direct Demonstration of P-Selectin– an...
This process is mediated in part by cellular adhesion molecules (CAMs) like vascular cell adhesion molecule-1 (VCAM-1), intercellular adhesion molecule-1 (ICAM-1), and E-selectin, expressed on the endothelial membrane, in response to several inflammatory cytokines, including interleukin-1, tumor ...