The limbic system, including the fornix, is heavily involved in the regulation of emotion and cognition [31,55]. This system has, however, not been extensively studied in HD [6]. An early study on seven HD cases showed loss of neurons in the entorhinal region and the subiculum, which ar...
The data are expressed as the average ± standard error of the mean (SEM). One-way analysis of variance (ANOVA) was performed, followed by a Sidak multiple comparison post hoc test as appropriate, to reveal the influence of the age of the Gaa−/−mice on the variables of interest...