The cause of irritable bowel syndrome is currently unknown. It is thought to result from a combination of abnormal gastrointestinal (GI) tract movements, increased awareness of bodily functions, and a disruption in the communication between the brain and the GI tract. IBS-D is irritable bowel syn...
作为RIP1激酶抑制剂用于治疗E.G.肠易激综合征(IBS)的N-[4-氧代-2,3-二氢-1,5-苯并氧氮杂 -3-基]-5,6-二氢-4H-吡咯并[1,2-B]吡唑-2-甲酰胺衍生物和有关化合物 [0001]相关申请的交叉引用 [0002]本申请要求于2018年4月20日提交的美国临时专利申请第62/660,397号的优先权权益,其内容通过引用...
complex pathophysiology of IBS and other FBDs: gut microenvironment (via diet and modulation of gut microbiota), enterohepatic circulation of bile acids, gastrointestinal secretion, motility and sensation, gut–brain interactions, gut barrier function and the immune system within the gastrointestinal tract...
The human body is a complex system, and one of its most fascinating connections is the gut-brain axis. This bidirectional communication between the gastrointestinal (GI) tract and the central nervous system (CNS) has recently gained traction in the scientific community, especially concerning acute n...