In a conclusion, our results suggested that DNA methylation and histone modifications (methylation and acetylation) synergistically regulate the chromatin construction, resulting in a compress and inac- tive, or loosened and active chromatin, and decide the tissue-specific regulation of rTert expression...
Various techniques, such as production of chimeric or humanized antibodies, may involve procedures of antibody cloning and construction. The antigen-binding Vκ (variable light chain) and VH (variable heavy chain) sequences for an antibody of interest may be obtained by a variety of molecular ...