Those COMT inhibitors which gain access to the brain would provide additional information about of the role of metabolism to potentiate brain dopaminergic and adrenergic functions. C Properties of the New Compounds Nitrocatechols have been described to be tight-binding inhibitors of COMT though their ...
painPain is an unfavorable feeling that is generally triggered by endogenous or exogenous harmful stimulation and has a strong emotional impact. The objective of this experimentation was to increase the cutaneous absorption of nortriptyline HCl (NOR) encapsulated in a niosome (norosomes) produced by ...