42. Kuo IC, Lee JJ, Hwang DY, et al. Pyuria, urinary tract infection and renal outcome in patients withchronic kidney disease stage 3-5. Sci Rep. 2020;10:19460. 43. Akkus? E, G?k?ay Canpolat A, Demir ?, ?orap??oglu D, S ...
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Most patients with intermediate-stage chronic kidney disease will develop secondary hyperparathyroidism before dialysis is required. Control of parathyroid hormone levels becomes a major focus of therapy in these patients. This article focuses on the position of extended-release calcifediol in the treatment...
2024年3月5日,FLOW研究的申办者诺和诺德公司宣布,提前终止的FLOW研究主要研究终点达成统计学显著性差异,司美格鲁肽1.0 mg治疗能够显著降低糖尿病合并CKD患者的肾脏结局终点和心血管死亡事件的发生率达26%,主要终点包括衡量CKD进展以及肾脏...
In Trial 1, the incidence of adverse reactions associated with renal function (acute kidney injury, serum creatinine increased, chronic kidney disease, creatinine clearance decreased, renal failure, renal impairment) was 3.6% (11/303) in ZEMDRI-treated patients compared with 1.3% (4/301) in mer...
TBS predicts fracture risk in chronic kidney disease, independently of BMD. 17. TBS predicts fracture risk in patients treated with glucocorticoid, independently of BMD. 18. TBS predicts fracture risk in rheumatological diseases, for example, rheumatoid arthritis, independently of BMD. 19. TBS ...
Diabetes Obes Metab. 2023 Nov;25(11):3327-3336. Estimated lifetime benefit of novel pharmacological therapies in patients with type 2 diabetes and chronic kidney disease: A joint analysis of randomized controlled clinical trials https://pubmed.ncbi.nlm.nih.gov/37580309/...
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间接作用:SGLT2i 还可改善多种代谢危险因素,如血糖、血压、血脂、血尿酸等,以及发挥内分泌效应,助力心肾获益[3,4](图 2、3)。 直接作用:通过心肌效应和血流动力学效应实现心血管获益[3](图 2);通过改善肾脏血流动力学、肾脏能量代谢、增加促红细胞生成素等途...