Lastly, a diet-induced diabetes in mice were applied to examine the efficacy and toxicity of hit natural phenolic products in long-term use (in vivo). After screening, curcumin, syringic acid, and resveratrol were found in high affinity with DPP IV enzymes. In enzymatic tests, curcumin and ...
We accommodated the animals in a continuous temperature- and humidity-controlled environment (22 ± 2 °C, 55 ± 5% humidity, and a 12-h light:12-h dark cycle), and fed them with Purina diet (Purina, Gyeonggi, Korea) and water, both provided ad libitum. This study was written in ...