Familial hypertrophie cardiomyopathy (HCM) is a rare autosomal dominant disorder linked to mutations of the cardiac myosin heavy chain genes. In obstructive HCM, systolic anterior motion of the mitral valve leaflet creates a subaortic pressure gradient. Echocardiography is the most useful study in ...
Everyone has read of the sudden, unforeseen death of an apparently healthy young person--sometimes a well-known athlete who collapses during a workout or game. The death is often described in the press as "inexplicable." Hypertrophic cardiomyopathy (HCM) is the likeliest explanation. It is in...
Credit: Pixabay/CC0 Public Domain Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiovascular condition. It is the leading cause of sudden cardiac death in young people and children, with an annual mortality rate of 1%. However, 10% to 20% of these patients have a significantly...
Hypertrophic cardiomyopathy (HCM) means "thickened heart muscle disease." It's the most common genetic (inherited) heart disease in the U.S. When you have it, the walls of your heart's left lower chamber are thicker than they should be. They can get stiff and sometimes scarred. This ...
Dilated cardiomyopathy can be a life threatening condition and can decrease life expectancy if severe damage occurs. Currently, the five-year survival rate for children diagnosed with dilated cardiomyopathy is between forty and eighty percent. The survival rate decreases if they child is diagnosed at ...
Hypertrophic cardiomyopathy (HCM) is a primary disorder of the cardiac muscle characterized by inappropriate myocardial hypertrophy of a nondilated left ventricle (LV) in the absence of a cardiovascular or systemic disease (i.e., aortic stenosis or systemic hypertension). ...
Hypertrophic cardiomyopathy (HCM) is a congenital cardiac disease with an estimated prevalence of 1:500 in the population. Individuals with HCM can present with clinical manifestations that include left ventricular outflow obstruction, cardiac dysrhythmias, diastolic heart failure, cardiac angina, and sud...
ContextThroughout the past 40 years, a vast and sometimes contradictory literature has accumulated regarding hypertrophic cardiomyopathy (HCM), a genetic
death in patients with hypertrophic cardiomyopathy include family history of sudden death (especially if in more than one family member), recurrent syncope, abnormal exercise blood pressure response (hypotension or failure of blood pressure to rise), and episodes of non-sustained ventricular tachycardia...
In most patients, hypertrophic cardiomyopathy is genetic with an autosomal dominant pattern of inheritance1–3. In something less than half of the cases, the disease is sporadic1; an unknown number of these cases, probably in younger patients, may repres