CKD is associated with various complications affecting multiple organ systems, leading to a significant reduction in health-related quality of life (HRQoL) when compared to the general population [10,12]. In hypertensive patients, symptoms such as headaches, chest pain, dizziness, and visual disturba...
Heart and kidneys are both target organ damage in hypertension. Left ventricular hypertrophy (LVH) is a sign of heart remodelling in people with hypertension. There are only few studies about correlation between type of LVH remodelling and chronic kidney disease (CKD). This study aims to know...
coronary heart disease (CHDcardiovascular disease (CVDchronic kidney disease (CKDglomerular filtration rate (GFRend stage renal disease (ESRDhigh‐density lipoprotein [HDL]‐cholesterol [HDL‐CClinical Epidemiology of Metabolic Syndrome Components and CKD...
CKD is associated with various complications affecting multiple organ systems, leading to a significant reduction in health-related quality of life (HRQoL) when compared to the general population [10,12]. In hypertensive patients, symptoms such as headaches, chest pain, dizziness, and visual disturba...
Diabetes/Kidney/Heart Disease Hypertension, kidney disease and APOL1: inextricably connected? The relationship between hypertension and CKD is complicated because they perpetuate each other. The cause of hypertensive renal disease is multifactorial. Long-term uncontrolled hypertension causes arteriolar nephrosc...
The efficacy and safety of renin-angiotensin system inhibitors (RAS-I) in hypertensive adults with non-diabetic chronic kidney disease (CKD) differ depending on the presence or the absence of proteinuria. To estimate the effects of RAS-I in this population, we performed a systematic review and ...
Tsukasa SUZUKI1), Yasuhiro KAWAGOE1), Yoshihiko UEDA3), Hikaru KOIDE4), and Koichi NODE2) The present study was conducted to compare the renal and vascular protective effects of telmisartan and amlodipine in untreated hypertensive chronic kidney disease (CKD) patients with moderate renal insuffi- ...
The FHS indicated that LVH is a strong risk factor for coronary heart disease, heart failure, and CV death [22]. Our results indicated that LVMI at CKD stages 3b–5 was elevated, compared to that at CKD stage 1. This is consistent with the observation that CV mortality is higher in ...
Activation of the renin-angiotensin system (RAS) is associated with hypertension and heart disease. However, how RAS activation causes cardiac lesions remains elusive. Here we report the involvement of Wnt/β-catenin signaling in this process. In rats with chronic infusion of angiotensin II (Ang ...
The patients with hypertension without heart failure, ischemic heart disease, cerebrovascular disease, or peripheral artery disease were enrolled. The CV events between only single prescription of CCBs and ARBs were finally compared. The primary endpoint for this study was the first occurrence of a ...