Simple hyperplasia is defined as an increase in the number of cell layers greater than normally present, and is frequently associated with an increase in mitosis and is sometimes accompanied by inflammation. Nodular hyperplasia (Figure 11.27) represents an endophytic growth, with epithelial cells ...
progressive growth that usually does not regress. Acollaretteof epithelium is defined as epithelium at the edge of a lesion, sometimes part of hyperplastic adnexal structures, that tends to bow inwardly and clutch alterations of the dermis. Examples of lesions that often have collarettes include lic...
is that anti-TSH receptor autoantibodies (TRAbs) promote TEC growth and unrestricted thyroid hormone T3 and T4 secretion by TSH mimics.5,6 However, treatment using rituximab to deplete TRAbs causes many side effects, such as aggravating ulcerative colitis.7,8 Thus, we believe that in addition ...
Early stages of carcinogenesis are characterized by incremental growth advantages, which are necessarily small in relation to normal tissues and exquisitely sensitive to environmental modification. Hormonally mediated selection20of latent transformed clones is one mechanism that ...
These cells subsequently serve as a source of SMCs that proliferate at the injured sites3,23. Notably, scavenger receptor-BI is closely linked to the role of rHDL10,24. In a study by Deiner et al., it was elucidated how the transfer of the VEGF gene into the adventitial region ...
(BPH) refers to the nonmalignant growth or hyperplasia of prostate tissue and is a common cause of lower urinary tract symptoms (LUTS) in older men. Disease prevalence has been shown to increase with advancing age. The histological prevalence of BPH at autopsy is as high as 50% to 60% ...
Benign prostatic hyperplasia is generally not regarded as a preventable disease. However, accumulating evidence suggests that modifiable factors may influe... Parsons,J Kellogg - 《J Urol》 被引量: 575发表: 2007年 Clinical, Anthropometric, Metabolic and Insulin Profile of Men with Fast Annual Grow...
Some studies indicate that the body’s system for working off testosterone slows in middle age. As a result, the body reacts by using this extra testosterone for the production of Dihydrotestosterone (DHT). High levels of DHT can cause enlarged prostate tissue growth. Diet Certain foods can ...
(EIC) is a recently described lesion characterized by replacement of endometrial surface epithelium or glands by malignant cells resembling high-grade invasiveendometrial carcinoma. Ambros et al.9have suggested that EIC is a form of intraepithelial tumor growth characteristic ofserous carcinomaand se...
The traditional view holds that hyperplasia of endocrine glands is secondary to oversecretion of a trophic hormone. However, in most cases, the mechanism underlying this growth is the spontaneous proliferation of benign neoplasias. Pathologists still depend on subtle morphological criteria to delineate ...