Define hypercholesterolemia. hypercholesterolemia synonyms, hypercholesterolemia pronunciation, hypercholesterolemia translation, English dictionary definition of hypercholesterolemia. n. 1. An excess of cholesterol in the blood. 2. A familial disorder c
Definition I. Hyperlipidemia is an increased level of lipid in the blood and is only physiologically relevant when it occurs in the fasted state. A. Hypertriglyceridemia is defined as a triglyceride concentration >150 mg/dL in dogs and >100 mg/dL in cats. B. Hypercholesterolemia is defined as...
We also evaluated the longer-term efficacy of evinacumab, 15 mg/kg, administered intravenously Q4W on lipid/lipoprotein parameters. LDL-C level was calculated using the Friedewald formula.11 This analysis was performed on the OL safety population comprising patients who received 1 or more doses...
A total of 14.699 patients (7.952 women and 6.747 men) fulfilled the criteria for the FH-P definition. LDL-c values in participants treated and untreated with LLT are shown in Fig. 2. Figure 1 Flow chart summarizing the participant selection in the study. LDL-c low-density lipoprotein ...
It seems to be a safe and efficacious approach in an attempt to lower the cholesterol levels in children with hyperlipidemia at high risk of early atherosclerotic disease, thus postponing the initiation of medical treatment. In addition, plant sterols do not decrease HDL-C concentration and ...
A definition of the medical term "hypercholesterolemia" is presented. Hypercholesterolemia refers to the excessive amount of cholesterol in the blood. The term originated from the words "chole" which means bile, "stereos" which means solid, and "haima" which means blood. The definition is from ...
Simplified Canadian Definition for Familial Hypercholesterolemia. Can. J. Cardiol. 2018, 34, 1210–1214. [Google Scholar] [CrossRef] [PubMed] Scientific Steering Committee on behalf of the Simon Broome Register Group. Mortality in treated heterozygous familial hypercholesterolaemia: Implications for ...
In the present study, we assessed the long-term efficacy and safety of evinacumab in HoFH patients on and off LA in real-world clinical practice. The primary outcome was the percentage changes in the calculated LDL-C from baseline to 24 months after evinacumab and LA treatment. The effect...
Apart from cholesterol, triglyceride is a type of fat converted by any excess calories from foods and mostly stored in fat cells for a longer-term energy source. A strong inverse correlation for triglyceride with HDL-C levels in this study further supports that hypertriglyceridemia leads to HDL-...
function, without causing disease [33]. However, the applicability of the term “likely” is limited to variants in which the data support a high probability of being pathogenic (>90%) or a high probability of being benign (>90%), without providing a quantitative definition of these aspects...