The blue color indicates an overall status of hypo-methylation, and the red color suggests hyper-methylation Full size image To investigate the molecular alterations of hyperhomocysteinemia (Hhcy) in diabetes by comparing the HM + STZ group with the STZ group, a total of 71,957 DMRs ...
DMRs were assigned to segmented regions using a Δβ cutoff of 0.3 (>0.3, hyper-methylated; < 0.3, hypo-methylated) and a significance of p < 0.05 (supplementaryData 1). We identified 1,269 DMRs for UD5 (947 kb of genomic regions), 1,149 for UD10 (1,211 kb) and 1,314 ...