PURPOSE. To evaluate the stability of a new, more convenient (<30 minutes for preparation), extemporaneously prepared hydroxyurea solution over 78 days. METHODS. A high-performance liquid chromatography (HPLC) method using a hydrophilic interaction chromatography (HILIC) column was developed and ...
cause the rabbits to produce megaloblastic cell similar as pernicious anemia and can inhibit leukocyte generation. In 1963 it had been found of its inhibitory effect on murine leukemia L1210. Hydroxyurea can induce bacteria to produce a toxic molecule itself to achieve the purpose of killing ...
PURPOSE: In 1986, a protocol comparing primary radiation therapy (RT) plus hydroxyurea (HU) to irradiation plus fluorouracil (5-FU) and cisplatin (CF) was ... CW Whitney,W Sause,BN Bundy,... - 《Journal of Clinical Oncology》 被引量: 2216发表: 1999年 Hydroxyurea for Patients with Essent...
Purpose To investigate a way to prevent postoperative adhesion and fibrosis after hang-back recession surgery, an animal study was carried out to evaluate the effect of mitomycin-C (MMC) and hydroxyurea (HU) on this procedure. Methods A prospective, masked-observer, controlled study was performed...
The purpose of this study is to perform and evaluate baseline abdominal ultrasound in infants with sickle cell anemia who participated in the BABY HUG mult... MB Mccarville,Z Luo,X Huang,... - 《Ajr American Journal of Roentgenology》 被引量: 221发表: 2011年 Effect of hydroxyurea treatment...
Purpose: Treatment of recurrent and progressive meningiomas remains a challenge in clinical neurooncology. This study was designed to evaluate the efficacy of the simultaneous application of 3d-conformal radiotherapy and chemotherapy with hydroxyurea (HU). Patients and methods: Twenty-one patients with re...
The purpose of this study was to test the hyp... MH Ellis - 《Journal of Allergy & Clinical Immunology》 被引量: 274发表: 1998年 The role of chemotherapy in the management of cancer of the head and neck: A review Although experience with drug therapy of advanced or recurrent squamous ...
As a result, a representative nano-flake was investigated in this work towards the drug design and delivery platform of an anticancer along with quantum chemical calculations of sumanene-hydroxyurea conjugations to provide details of a proposed systems for approaching a possible medication purpose. ...
QUINOLIN-2-YL-METHOXYBENZYLHYDROXYUREAPURPOSE: To provide a new compd. which acts as a lipoxygenase inhibitor in a arachidonic acid metabolism and is useful for the therapy and prophylaxis for allergic airway diseases, various kinds of inflammation and thrombosis.MATZKE MICHAEL DR...
PURPOSE OF REVIEW: Sickle cell anemia (SCA) is a well characterized severe hematological disorder with substantial morbidity and early mortality. Hydroxyurea is a potent inducer of fetal hemoglobin, and evidence over the past 25 years has documented its laboratory and clinical efficacy for both ...