Somatic copy number alteration might be the main cause of the negative correlation between HSD17B6 expression and immune infiltration. HSD17B6 expression in HCC negatively correlated with the expression of several immune cell markers, including exhausted T cell markers, PD-1 and CTLA-4, suggesting ...
3α-Hydroxysteroid dehydrogenase(3α-Hydroxysteroid: NAD(P) oxidoreductase, EC 1.1.1.50) catalyses the following reaction: (1)3α-Hydroxysteroid+NAD+⇌3-Ketosteroid+NADH+H+ 3ß,17ß-Hydroxysteroid dehydrogenase (3(or 17)ß-Hydroxysteroid: NAD(P) oxidoreductase, EC 1.1.1.51) catalyses ...
The 17β-hydroxysteroid dehydrogenase enzymes (17β-HSDs, EC1.1.1.62) catalyze the NAD(P)(H) dependent oxidoreduction of hydroxyl/keto groups at position C17 of androgens and estrogens and in this manner regulate intracellular availability of steroid hormone ligands to their nuclear receptors. This...
17beta-Hydroxysteroid dehydrogenase (17beta-HSD) from the filamentous fungus Cochliobolus lunatus (17beta-HSDcl) catalyses the reduction of steroids and of several o- and p-quinones. After purification of the enzyme, its partial amino acid sequence was determined. A PCR fragment amplified with pri...
英文别名: HSD17B13 (Hydroxysteroid (17-beta) Dehydrogenase 13, SCDR9, NIIL497, SDR16C3, HMFN0376, 17 Beta hydroxysteroid Dehydrogenase 13) (AP)中文名: 中文别名: CBNumber: CB04949071 分子式: 分子量: 0 MOL File: Mol file 化学性质 安全信息 用途 供应商 1 HSD17B13 (Hydroxysteroid (17-...
( 1999 ) Characterization of 17β-hydroxysteroid dehydrogenase activity in the human brain . J. Neuroendocrinol. 6 , 457 – 464 ... Steckelbroeck,Stoffel-Wagner,Reichelt,... - 《Journal of Neuroendocrinology》 被引量: 65发表: 2001年 Characterization of 17 beta-hydroxysteroid dehydrogenase activit...
3-hydroxysteroidaldo-keto reductasedehydrogenasesecosteroidsshort-chain dehydrogenases/reductasesThe patient was admitted to our hospital at 19 and again at 22-yr of age for hirsutism and hypertension. Her baseline and ACTH-stimulated plasma 17-hydroxy pregnenolone, dehydroepiandrosterone and dehydro...
内异症组类固醇类产生因子-1(steroidgenic factor-1,SF-1)、小鸡卵清蛋白上游启动转录因子(chicken ovalbumin upstream-transcription factor,COUP-TF),17-β-羟甾类脱氢酶1(17-beta-hydroxysteroid dehydrogenase 1,17-β-HSD 1)和17-β-羟甾类脱氢酶2(17-beta-hydroxysteroid dehydrogenase 2,17-β-HSD 2)...
17beta-hydroxysteroid dehydrogenase type 1 (17β-HSD1) is a steroidal enzyme which, in breast cancer cells, mainly synthesizes 17-beta-estradiol (E2), an e... JA Aka,EL Calvo,SX Lin - 《Molecular & Cellular Endocrinology》 被引量: 0发表: 2017年 Progestin regulation of 11beta-hydroxystero...
Objective To investigate the expression of 17βhydroxysteroid dehydrogenase type 2(17βHSD2) in the eutopic endometrium and endometriotic tissue of endometriosis. 目的探讨17β-羟类固醇脱氢酶2(17βHSD2)在子宫内膜异位症(内异症)在位与异位内膜的表达与发病的关系。2...