Based on clearance studies of nonpregnant animals, 25 mg of 17-OHPC was administered at 6-day intervals to a test group of 31 pregnant monkeys while the control group of 29 received saline. Venous blood was obtained at 6- to 12-day intervals for measurement of 17-hydroxyprogesterone (17-...
Methods Serum 17OHP was measured in peripheral venous blood between 3rd to 5th day of life by competitive radioimmunoassay and on follow up at 3 mo of age. Serum 17OHP was compared among four groups [full term healthy(FT), full term stressed(FS), preterm healthy(PT), preterm stressed(PS...
as such, samples of newborns on filter paper from ramon gonzalez coro hospital were collected and analyzed.the blood spots from a sample were classified according to their appearance, satisfactory spot (mv) or unsatisfactory spot (mnv). phe and 17ohp levels were determinated by umtest pku and ...
An enzyme immunoassay of 17伪-hydroxyprogesterone (17-OHP) in dried blood spotted onto filter paper has been developed. 17-OHP was conjugated to horseradis... H Arakawa,M Maeda,A Tsuji,... - 《Chemical & Pharmaceutical Bulletin》 被引量: 51发表: 1983年 Development of an ELISA-based kit ...
The study was conducted at both Children's National Medical Center and Georgetown University using outpatient blood samples obtained between January 1, 2004 and June 30, 2008. METHODS: Serum samples were analyzed using isotope dilution liquid chromatography tandem mass spectrometry (LC/MS/MS) with ...
This may have been due to the fact that only a moderate increase of this steroid in blood plasma was induced. However, our results suggest an interaction between DOC and MIS, resulting in increased milt hydration. To test whether this could possibly involve an indirect effect of DOC through ...
17α-Hydroxyprogesterone (17α-OHP) quantification in dried blood spots (DBS) is essential for newborn screening for congenital adrenal hyperplasia
However, only infants who were treated with multiple antenatal courses of steroids had lower blood 17-OHP than those who were untreated (p <0.05 with the Mann-Whitney U test). In multiple regression analysis, steroid treatment and intrauterine growth retardation were significant negative predictors ...
test.Results: Whole blood treated with 17-P or progesterone in addition to LPS produced significantly higher TNF-α concentrations than blood treated with LPS alone.Conclusion: 17-P and progesterone appear to have a pro-inflammatory effect during LPS stimulati...
Examination program consisted of a clinical examination, completion of a self-administered questionnaire and blood sampling. Steroid metabolites were measured by a validated and sensitive LC–MS/MS method. Older age-groups were significantly associated with decreased concentrations of DHEA, DHEAS, Adione...