Disclosed are: isolated, pure DNA comprising at least one domain encoding a polypeptide associated with the hydroxylation of vitamin D; a polypeptide encoded by the DNA; a autonomously or integratively replicating recombinant plasmid carrying the DNA; a transformant having the DNA; and a method for...
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The ability to 25-hydroxylate vitamin D was investigated in thirty-nine patients with symptomatic primary biliary cirrhosis (P.B.C.). In seven previously untreated patients serum-25-hydroxyvitamin-D (25-OHD) concentration increased after regular monthly injections of vitamin D. After a single inje...
L. ManciniUniversity of BariM. CarrozzoUniversity of BariSpringer-VerlagClinical RheumatologyCantatore FP,Loperfido MC,Magli DM,et al.The Importance of vitamin C for hydroxylation of vitamin D3to 1,25(OH)2D3 in man[J].Clin Rheumatol,1991,10:162-167....
1,25(OH)2D3,1,25-dihydroxyvitamin D3D, vitamin DThe liver microsomal C-25 hydroxylation of [3H]-vitamin D3 was evaluated in 19- and 22-day-old rat fetuses, and in 1-, 2-, 3-, 14-, 30-, and 60-day-old pups. The hepatic production of [3H]-25-hydroxyvitamin D3 by the 19...
Microsomal C-25 Hydroxylation of [3H]-Vitamin D3by the Fetal and Neonatal Rat Liver VICTOR PLOURDE, PIERRE HADDAD, AND MARIELLE GASCON-BARRE Centre de Recherches Cliniques, Centre Hospitalier Saint-Luc and Departement de Pharmacologie, Faculte de Medecine, Universiti de Montreal, Montreal, Quebec...
CYP11A1 can hydroxylate vitamin D3 at carbons 17, 20, 22, and 23, producing a range of secosteroids which are biologically active with respect to their ability to inhibit proliferation and stimulate differentiation of various cell types, including cancer cells. As 1 alpha-hydroxylation of the ...
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Isolation of a cytochrome P-450 that catalyzes the 25-hydroxylation of vitamin D3 from rat liver microsomes A molecular species of cytochrome P-450 that catalyzes the 25-hydroxylation of cholecalciferol (P-450cc25) was purified from rat liver microsomes on the ba... S Hayashi,M Noshiro,K Ok...
Define hydroxylation. hydroxylation synonyms, hydroxylation pronunciation, hydroxylation translation, English dictionary definition of hydroxylation. tr.v. hy·drox·yl·at·ed , hy·drox·yl·at·ing , hy·drox·yl·ates To introduce hydroxyl into . hy