Intracellular recording techniques were used on spinal motoneurons in the cat in order to define the synaptic pharmacology of 11-hydroxy-delta-9-tetrahydrocannabinol (11-hydroxy-delta-9-THC), the principal metabolite of delta-9-tetrahydrocannabinol (delta-9-THC). The 11-hydroxy derivative increased ...
(2005) Simultaneous analysis of the Delta9-THC metabolites 11-nor-9-carboxy-delta9-THC and 11-hydroxy-delta9-THC in meco- nium by GC-MS. Journal of Analytical Toxicology, 29, 522-527.Simultaneous analysis of the Δ 9 -THC metabolites 11-nor-9-carboxy-Δ 9 -THC and 11-hydroxy-Δ 9...
GPCR/G Protein; Neuronal Signaling; Metabolic Enzyme/Protease储存⽅式: Please store the product under the recommended conditions in the Certificate of Analysis.BIOLOGICAL ACTIVITY⽣物活性10α-hydroxy-exo-THC 是⼀种⼤⿇素类化合物 (phytocannabinoid),是Δ9-THC 的代谢物,可在⼤⿇中被发现。
The formation of 7-oxo-Delta (8)-tetrahydrocannabinol (7-Oxo-Delta (8)-THC from 7 alpha- or 7 beta -hydroxy-Delta (8)-THC (7 alpha- or 7 beta -OH-Delta (8)-THC) was found in hepatic microsomes of monkeys. The activity in 7 beta -OH-Delta (8)-THC was stereoselectively 2.5-...
287 Benzoylecgonine (BZE) and 11-nor-Δ9-tetrahydrocannabinol-9-carboxylic-acid (THC-COOH), the primary metabolites of cocaine and Δ9-tetrahydrocannabinol, were extracted from urine using SPE with 10 mg C18.281,288 Additional drugs of abuse extracted from urine, using a cartridge containing 10...
BACKGROUND: Whole blood, plasma and urine delta-9-tetrahydrocannabinol (THC), 11-hydroxy-THC (11-OH-THC) and delta-9-carboxy-THC (THCCOOH) concentrations document cannabis exposure. Clinical data generally are derived from specimens obtained after single THC administrations. Few data are available...
Whole blood, plasma and urine Delta9-tetrahydrocannabinol (THC), 11-hydroxy-THC (11-OH-THC) and Delta9-carboxy-THC (THCCOOH) concentrations document cannabis exposure. Clinical data generally are derived from specimens obtained after single THC administrations. Few data are available from daily ...
Handrick et al., Hashish: Synthesis of (-)-Delta9-tetrahydrocannabinol (THC) and its biologically potent metabolite 3'-hydroxy- Delta9-THC, Tetrahedron Lett., No. 8, pp. 681-684 (1979).G.R. Handrick, D.B. Uliss, H.C. Dalzell, R.K. Razdan, Hashish: synthesis of (-)-Δ9-...
(-)-Delta-9-tetrahydrocannabinol ((-)-Delta-9-THC) is the main psychoactive constituent in cannabis. During phase I metabolism, it is metabolized to (-)-11-hydroxy-Delta-9-tetrahydrocannabinol ((-)-11-OH-Delta-9-THC), which is psychoactive, and to (-)-11-nor-9-carboxy-Delta-9-...
Synthesis and characterization of glucuronides of 5′-hydroxy-delta-9-THC and 11-hydroxy-delta- 9-THC. Drug Met Disp 1978;6:389-95.Pallente S, et al. Synthesis and Characterization of Glucuronides of 5'-Hydroxy-delta-9-THC and 11-Hydroxy- delta-THC. Drug Metab Dispos. 1978 Jul-Aug;...