Hydrophilic interaction liquid chromatography: some aspects of solvent and column selectivity. Download technical note › Get started with HILIC HILIC separations: a practical guide to HILIC mechanisms, method development and troubleshooting. Download brochure › HILIC in bioapplicati...
Today, the most rational way to address the separation of very hydrophilic and uncharged compounds in HPLC is by utilizing hydrophilic interaction liquid chromatography (HILIC), which is considered to be a variant of normal-phase chromatography. According to McCalley, stationary phases used for ...
Hydrophilic interaction liquid chromatography (HILIC :亲水作用色谱(HILICHILIC,亲水作用 文档格式: .pdf 文档大小: 1009.81K 文档页数: 17页 顶/踩数: 0/0 收藏人数: 1 评论次数: 0 文档热度: 文档分类: 论文--毕业论文 文档标签: HILIC亲水作用
In the early 1990s, hydrophilic interaction (liquid) chromatography (HILIC) emerged as a new separation method. HILIC is becoming increasingly popular for the separation of polar compounds in aqueous-organic mobile phases rich in organic solvents (usually acetonitrile). It has become important for the...
Pedanou E, Hong P, Lander N. Hydrophilic Interaction Liquid Chromatography (HILIC) Method Migration Part 1: From Legacy HPLC Systems to the Alliance™ iS HPLC System. Waters Application Note.720007993. June 2023. Malm M, Kjells...
Hydrophilic interaction liquid chromatography (HILIC) in proteomics In proteomics, nanoflow multidimensional chromatography is now the gold standard for the separation of complex mixtures of peptides as generated by in-solu... PJ Boersema,S Mohammed,AJR Heck - 《Analytical & Bioanalytical Chemistry》 ...
Lack of familiarity with hydrophilic interaction liquid chromatography (HILIC) methods, which are known for their unique and complex separation mechanisms, can pose challenges for system set ups given the differences in strong and weak ...
Hydrophilic interaction liquid chromatography-mass spectrometry for cinnamic acid determination and its use to evaluate components of dried hot peppers (Capsicum annum) associated with growth inhibition of Salmonella enterica serovarsdoi:10.1111/jfbc.12342...
Hydrophilic interaction liquid chromatography (HILIC) has become in the last years a leading technique for the separation of small and large polar molecules. This chapter begins with a discussion about the most relevant characteristics of this chromatographic mode that makes HILIC a complementary and, ...
In this work a hydrophilic interaction liquid chromatography/positive ion electrospray mass spectrometric assay (HILIC/ESI-MS) has been developed and fully validated for the quantitation of metformin and rosuvastatin in human plasma. Sample preparation involved the use of 100 μL of human plasma, foll...