By analyzing the formation of 4 under various conditions, the presence of numerous primary amines in a PAMAM dendrimer did accelerate the hydrolysis of peripheral boronic acid. This investigation revealed an apparent intrinsic problem that needs to be overcome during the preparation of boronic acid-...
ChemInform Abstract: Stereoselective Hydrolysis of p‐Nitrophenyl Glycoside by Boronic Acidcarbohydratesstereochemistry (general, optical resolution)solvolysis, hydrolysisChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To ...
In contrast, the rate of hydrolysis of imine 3 is unaffected by added saccharides.doi:10.1016/s0040-4039(99)00225-7James H. HartleyTony D. JamesTetrahedron LettersSaccharide accelerated hydrolysis of boronic acid imines[J] . James H. Hartley,Tony D. James.Tetrahedron Letters . 1999 (13)...
We decided to investigate how the Lewis acidity of integrated boronic acids affects the rate of hydrolysis of simple imines.8It has been known for over forty years that the boron atom in a boronic acid becomes more acidic when bound to a saccharide.9This is due to the reduction in the O...
Hydrolysis of adduct of boronic acid and diethanolamine; by-product inhibition; thrombosis; anticoagulantsdoi:US20050119226 A1Organoboronic acids, for example Cbz-(R)-Phe-(S)-Pro-(R)-Mpg-B(OH) 2 , are made by hydrolysing their diethanolamine adducts under conditions which avoid substantial C—...
Accelerated hydrolysis of boronic acid in a modified poly(amidoamine) dendrimer: identification of a factor leading to the production of an impurity in boronic acid containing poly(amidoamine) dendrimersboronic aciddendrimershydrolysis11B NMRproximity...
Additionally, a commercial sample of '8-quinolylboronic acid' was actually found to be the anhydride. The results call into question whether monomeric (quinolin-8-yl)boronic acid can actually be isolated in the neutral Lewis base-free form....
The method was applied to successfully resolve ten different boronic acid and boronic pinacol ester functionalized compounds within five minutes. Thus, the wide range applicability of fast RPLC technology for accurate analysis of this specific class of compounds was demonstrated.doi:10.1080/...
Stereospecific acceleration of hydrolysis toward the a-anomer over the g- anomer then increased to a high extent. The effect of the type of boronic acid in micelles of HTAC was examined in order to clarify the mechanism of the enhancement of the hydrolysis rate of the alpha-glucoside and the...
ChemInform Abstract: Stereoselective Hydrolysis of p-Nitrophenyl Glycoside by Boronic Acid.carbohydratesstereochemistry(generalopticalresolution)solvolysishydrolysisChemInform is a weekly ing Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ...