Ingestion of low concentrations of hydrogen peroxide (H_2O_2) is generally benign. However, serious toxicity such as venous/arterial gas embolism, hemorrhagic gastritis, and death, has been reported with higher concentrations. A concentration of 35% or greater, sometimes used to treat various ...
Hydrogen Peroxide H2O2 Poisoning: Air in the Liver Hydrogen peroxide (H2O2) is an oxidizing agent with lots of domestic and industrial applications. Its accidental ingestion can cause toxicity by three diff... YC Spolverato,M Zuin,M Valmasoni,... - 《Indian Journal of Surgery》 被引量: 0...
hydrogen peroxide is corrosive to the eyes and can cause severe irreversible damage and possibly blindness. Hydrogen peroxide is moderately toxic by ingestion and slightly toxic by inhalation. This substance is not considered to have adequate warning properties. Hydrogen peroxide has not been found to...
DNA, and cell membrane lipids - both bacteria/viruses and tissue.[6]Hydrogen peroxide may be harmful with dermal or ophthalmic exposure, ingestion, wound or rectal irrigation, injection, or inhalation. The toxicity depends on the solution's concentration type of exposure.[2] ...
At greater than 10% concentration, hydrogen peroxide is corrosive to the eyes and can cause severe irreversible damage and possibly blindness. Hydrogen peroxide is moderately toxic by ingestion and slightly toxic by inhalation. This substance is not considered to have adequate warning properties. ...
Concentrated hydrogen peroxide has caustic effects, and ingestion should be treated like a caustic exposure. Endotracheal intubation for patients who have symptoms of upper airway obstruction should be considered. There is no antidote for hydrogen peroxide toxicity, and hemodialysis, hemoperfusion, and ...
Hydrogen peroxide is a commonly used oxidizing agent with a variety of uses depending on its concentration. Ingestion of hydrogen peroxide is not an uncommon source of poisoning, and results in morbidity through three main mechanisms: direct caustic injury, oxygen gas formation and lipid peroxidation...
Toxicity Oral LD50 in mouse is 2000 mg/kg, and dermal LD50 is 4060 mg/kg in rat and 2000 mg/kg pig. LC50 of hydrogen peroxide vapours in rat is 2000 mg/m at 4 hours MSDS. Oral ingestion of high dose hydrogen peroxide may cause chest and stomach pain, loss of consciousness, motor ...
Hydrogen peroxide (H2O2) is an endogenous ROS produced by mitochondria through the dismutation of superoxide (O2.−) by mitochondrial superoxide dismutase (SOD2), and also outside the mitochondria by cytoplasmic oxidases18,19. H2O2is relatively stable and freely diffusible, and in neurons mitochond...
The pediatric population (< 18 years) accounted for 71% of hydrogen peroxide exposures and ingestion was the most common route of exposure (83%). Nausea and vomiting were the most common symptoms secondary to ingestion. Ocular and dermal exposures to dilute solutions resulted in transient symptoms...