The hydrogen bonds in DNA Watson–Crick base pairs have long been considered predominantly electrostatic phenomena. In this chapter, we show with state-of-the-art calculations that this is not true and that electrostatic interactions and covalent contributions in these hydrogen bonds are in fact of...
DNA structures •Hydrogen bonds •Resonance assistanceWe challenge the view that the hydrogen bonds in Watson–Crick AT and GC base pairs are in essence electrostatic interactions with substantial resonance assistance from the π electrons. Instead, based on detailed analyses of the hydro...
How to break hydrogen bonds in DNA DNA: DNA is an information carrier molecule used by living cells to direct the process of gene expression. It is comprised of a double helix of two strands in which the DNA bases interact via hydrogen bonding. ...
Cite this chapter Guerra, C.F., Bickelhaupt, F.M. (2006). Substituent Effects on Hydrogen Bonds in DNA. In: Šponer, J., Lankaš, F. (eds) Computational Studies of RNA and DNA., vol 2. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-4851-3_18 Download citation .RIS ...
Altered Minor-Groove Hydrogen Bonds in DNA Block Transcription Elongation by T7 RNA PolymeraseDNAmodificationsmismatchesRNApolymerase Meyer,Fabian,Spivak,... - 《Chembiochem A European Journal of Chemical Biology》 被引量: 0发表: 2015年 Transcript cleavage by RNA polymerase II arrested by a cyclobutane...
Hydrogen bonds are found in DNA between the nitrogenous base pairs that connect the two nucleotide chains, forming a double helix. DNA, or...Become a member and unlock all Study Answers Start today. Try it now Create an account Ask a question Our experts can answer your tough homework ...
We have theoretically analyzed mimics of Watson-Crick AT and GC base pairs in which N-H···O hydrogen bonds are replaced by N-H···S, using the generalized gradient approximation (GGA) of density functional theory at BP86/TZ2P level. The general effect of the above substitutions is an...
quantifying and clearly demarking H-bonding difficult. The low strength of (most) H-bonds in ILs makes them dynamic, able to form and break at room temperature. The characteristics and features of H-bonding in ILs cover an extremely wide and diverse range, and are not well understood [1,...
Hydrogen bonding greatly affects our biology. Numerous examples in biochemistry show how important hydrogen bonding is. In DNA, hydrogen bonds between nitrogenous bases in nucleotides on the two strands of (guanine pairs with cytosine, adenine with thymine) give rise to the double-helix structure tha...
Hydrogen Bonds in DNA Molecules DNA strands are held together into a double helical structure by hydrogen bonds between the purine and pyrimidine bases on the two complementary strands. This highly specific base pairing of A-T (two hydrogen bonds) and G-C (three hydrogen bonds) was instrumental...