Herein, innovative hydrogel bioinks were developed by combining nanofibrillated cellulose (NFC) with a fucose-rich polysaccharide, FucoPol (FP), still unexplored for 3D bioprinting. NFC/FP bioinks with different mass proportions, namely 1:1, 2:1, 3:1 and 4:1, were prepared and denominated as...
Furthermore, the integration of nanoparticles into hydrogel-based bioinks imparts “smart” features to these materials, endowing tissue constructs with the ability to respond to external stimuli. This responsiveness adds a layer of precision and adaptability to the treatment process, underscoring the p...
This review provides an in-depth discussion of the aspects involved in in situ bioprinting for skin regeneration, including crosslinking mechanisms, properties of natural and synthetic hydrogel-based bioinks, various in situ bioprinting methods, and the clinical translation of in situ bioprinting. The ...
and affordability of the bioinks are also taken into consideration during 3D printing of cell laden scaffolds16. During 3D printing, less viscous bioinks easily flow through the narrow printing nozzle but they have the drawbacks of smearing and low shape fidelity12,19. Highly viscous bioinks can g...
The healthcare industry has witnessed great achievements owing to the use of functionalized bioinks. Accordingly, for over 2 decades, researchers have been working on improving the autologous skin substitutes for human dermal, epidermal, and loss of skin tissue after injury. With the addition of 3D...
One of the greatest challenges in the field of biofabrication remains the discovery of suitable bioinks that satisfy physicochemical and biological requirements. Despite recent advances in tissue engineering and biofabrication, progress has been limited to the development of technologies using polymer-based ...
To address potential stability issues and explore the feasibility of fabricating bioinks with cells incorporated into the polymer mixtures, we tested the same compositions using PBS as the solvent instead of water for the polymers employed in this study [48]. Both moulded and bioprinted scaffolds pre...
This powerful approach to deconstruct bulk hydrogels into advanced bioinks is both scalable and versatile, representing an important toolbox for 3D bioprinting of architected hydrogels. 中文翻译: 基于缠结水凝胶微丝的大孔材料3D生物打印 水凝胶是哺乳动物细胞外基质的优异模拟物,并在组织工程中得到广泛应用...
To produce a 3D structure that is biologically functional, cell-laden bioinks must be optimized to meet certain key characteristics including rheological properties, physico-mechanical properties, and biofunctionality; a difficult task for a single component bioink especially for extrusion based bioprinting...
This review also summarizes various bioprinting techniques, the gelation and biodegradation mechanisms of hydrogel-based bioinks, the properties required for ideal bioink, challenges to design bioinks, as well as reviews the fabrication of 3D printed cardiac tissue, cartilages, brain-like tissue, bionic...