Disclosed herein is a hydrogel that eradicates biofilm bacteria from wounds and accelerates diabetic wound healing. Also disclosed herein are methods of manufacture and use of said hydrogel.Bee Eng Mary CHANChun Kiat YEONguan Soon TANSurendra Hittanahalli MAHADEVEGOWDA...
Therefore, the design of an effective wound dressing is a major perquisite to enhance the healing rate of wounds. A proper wound dressing should provide a favorable micro-environment for wound healing via an appropriate gas exchange with the environment, while not permeable to dust particles and ...
Overall, this work demonstrates the facile preparation of a new dynamic hydrogel system, presenting a promising solution for wound care therapy as an antioxidative wound dressing. This work introduces a self-healing, antioxidative hydrogel with rapid gelation, offering enhanced effectiveness for chronic ...
So the gel can create a moist wound management environment, which is propitious for wound healing. Benefits: Crystal clear transparency for easy accurate visualization wound assessment; Maintaining hydration balance to provide moist wound environment for healing; Encouraging wound autolytic debrideme...
woundhealingIn article number 1801386, Jianan Ren, Yuanjin Zhao, and co‐workers report a bioinspired multifunctional hybrid hydrogel encapsulating vascular endothelial growth factor. Mixing of four‐armed benzaldehyde‐terminated polyethylene glycol and dodecyl‐modified chitosan forms the gel. The hydrogel...
Moist healing: The high water content of this dressing can not only provide the required moisture for the wound, but also absorb exudate from the wound to maintain a moist environment on the wound, thereby promoting wound healing.Autolyti...
"The oxygen has two roles: One, to improve skin cell survival under the low-oxygen condition of the diabetic wound; and two, oxygen can stimulate the skin cells to produce growth factors necessary for wound repair," Guan said. Tissues in the body require oxygen to survive and need even mo...
Fig. 5: Crosslinking of GelMA hydrogel dressing modulates fibroblast function and collagen deposition in wound healing. a UMAP representation of fibroblasts from lo- or hi-GelMA and Sham-treated wounds were categorized into six subpopulations presented by UMAP, with each cell color-coded for its as...
focus on the potential application of smart responsive hydrogels in diabetic wound healing (Fig.1). In short, this review is intended to contribute to the ongoing work to promote hydrogels towards ideal dressing for diabetic wound healing which might be beneficial for clinical application of ...
The effects of the hydrogel on wound closure was evaluated in a mouse model as reported34. Briefly, a drop of 1.0%-BG/OSA or pure OSA gelling solution was used on the wound edge. Then, the two wound edges were brought in contact for 1 min. Chronic wound healing in vivo Female...