We particularly focus on the use of anatomy and physiology-based imaging techniques and diffusion tensor imaging which are supported by a growing body of literature as promising noninvasive tools in the diagnosis and long-term management. We conclude with a brief discussion on more novel, emerging...
The first known reports of “water” around the brain of macrocephalic children comes from Hippocrates, although the term “hydrocephalus” was not coined until the writings of Celsus sometime between 25 BC to 50 AD [1,2]. Though little was initially known about the anatomy and physiology of...
Though little was initially known about the anatomy and physiology of this captivating problem, anatomists like Galen and Antyllus attempted the earliest surgery with expectedly poor outcomes [1]. Further elucidation of the condition came more recently from the early modern era of seventeenth century...
The choroidal fissure: anatomy and surgical implications. Advances and technical standards in neurosurgery 38, 97–113 (2012). 23. Bakker, E. N. et al. Lymphatic Clearance of the Brain: Perivascular, Paravascular and Significance for Neurodegenerative Diseases. Cellular and molecular neurobiology 36...
Anatomy and Physiology To understand Normal Pressure Hydrocephalus (NPH), a basic knowledge of the anatomy and physiology of the brain is helpful. The brain occupies most of the space inside the skull and is surrounded by a cushioning layer of cerebrospinal uid (CSF). CSF is a clear ui...
whereas other children may display relatively normal anatomy associated with a web obscuring CSF flow. Genetics factors contributing to AS includeATP1A3, which encodes an ATPase ion channel that has been associated with CNS development and ventricular dilatation when disrupted in zebrafish [34]. In ...
Preuss M,Hoffmann KT,Reiss-Zimmermann M,Hirsch W,Merkenschlager A,Meixensberger J,Dengl M, Updated physiology and pathophysiology of CSF circulation--the pulsatile vector theory. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery. 2013 Oct;[Pu...
Department of Anatomy and Cell Biology, Temple University School of Medicine, Philadelphia, 19140, Pennsylvania, USA Raehee Park, Uk Yeol Moon, Jun Young Park, Seo-Hee Cho & Seonhee Kim Graduate Program of Biomedical Sciences, Temple University School of Medicine, Philadelphia, 19140, Pennsylvania...
What follows is a broad overview of CSF anatomy and physiology, a simple classification of the causes of hydrocephalus, a description of the mode of presentation and a summary of contemporary surgical management.doi:10.1016/j.mpsur.2009.02.005Dominic N.P. Thompson...
neural-immune cross talk is an essential component of health and physiology but can become maladaptive, especially in a brain primed by pre-existing inflammation or prior insult [96]. Immune plasticity altered by hydrocephalus may also have long-term effects. The persistent presence of soluble infla...