Twitter Google Share on Facebook Hyalgan® Orthopecis A hyaluronate used to treat osteoarthritic knee pain in Pts unresponsive to conservative therapy or simple analgesics; it is injected directly into the knee; relief lasts up to 6 months. SeeOsteoarthritis. ...
Intra-articular hyaluronic acid in the treatment of osteoarthritis of the knee: A long-term study3 Study design 30-month, repeat-use, open-label study (N=75) of IA HYALGAN®20mg weekly x5, repeated every 6 months for 5 treatment cycles. One cycle=5 injections. A total of 5 IA inject...
Efficacy and Safety of Intra-articular Injections of Sodium Hyaluronate (Hyalgan®) in the Treatment of Osteoarthritis of the KneeBackground: The efficacy and tolerability of 500-730 kDa sodium hyaluronate (Hyalgan(R)) for treatment of osteoarthritis (OA) pain has been established in clinical ...
The efficacy of intra-articular Hyalgan® injections as a treatment for the pain of OA is likely due, in part, to the dramatic reduction of inflammatory macrophages via reduced proliferation and induced apoptosis, as presented in this study. Chronic inflammatory reactions, as in OA, are charact...
Background: Intra-articular (IA) hyaluronan (HA) injections are approved for the treatment of knee osteoarthritis (OA) pain. One of the currently available... D Amiel,T Toyoguchi,K Kobayashi,... - 《Osteoarthritis & Cartilage》 被引量: 374发表: 2003年 ...
Postural stability is critical for mobility and physical activities. Current treatments for knee OA are analgesics or nonsteroidal anti-inflammatory drugs (NSAIDs), surgical treatments, intra-articular injections, physiotherapy, weight reduction, exercise, orthotic (braces), and patient education. ...
It is a major cause of pain, disability and handicap, and a difficult condition to treat. Pharmacological treatment has been limited to the use of analgesics, non-steroidal anti-inflammatory drugs and the controversial use of intra-articular steroid injections. None of these options provide a ...
Pain MeasurementTreatment OutcomeAdministration, OralInjections, Intra-ArticularDouble-Blind MethodHyaluronic AcidTo determine efficacy and safety of intraarticular (IA) hyaluronic acid (HA; Hyalgan) versus placebo and a nonsteroidal antiinflammatory drug for osteoarthritis (OA) of the knee. A series of...
The present study suggests that five weekly intra-articular injections of sodium hyaluronate are well tolerated, can provide sustained relief of pain, and can improve function in Asian patients with osteoarthritis of the knee. Level of Evidence Therapeutic study, Level I-1a (randomized controlled tria...
MATERIALS AND METHODS: Thirty consecutive patients with ankle OA documented by X-ray were randomized to treatment with five weekly injections of either sodium hyaluronate 2 mL (HYL) or phosphate-buffered saline 2 mL (control) in the tibiotalar joint. The primary endpoint was pain on movement ...