Y-27632 dihydrochloride,HY-10583,MCE: Description Y-27632 dihydrochloride is a cell-permeable, ATP-competitive inhibitor ofROCK-IandROCK-II, withKis of 220 and 300 nM, respectively. IC50& Target ROCK-I 220 nM (Ki) ROCK-II 300 nM (Ki) ...