其中,基础培养基为无血清IMDM培养基;内胚层细胞诱导分化因子包括EGF,FGF2,丁酸钠和Wnt信号通路激动剂;肝前体细胞诱导分化因子包含FGF2,HGF和ITSX,肝成熟细胞诱导分化因子包含抑瘤素M,地塞米松和ITSX.使用本发明的化学成份明确的体外诱导体系对第4代hWJMSCs细胞进行诱导后,细胞形态呈现成熟肝细胞典型的双核特征,表达上...
Co-culture of hWJMSCs and pACs in double biomimetic ACECM oriented scaffold enhances mechanical properties and accelerates articular cartilage regeneration in a caprine modelAcellular cartilage extracellular matrix-oriented scaffoldHuman umbilical cord Wharton’s jelly-derived mesenchymal stem cellPrimary ...
Human Wharton's jelly mesenchymal stem cell-conditioned medium (hWJMSCs-CM) possesses anticancer, wound healing, cerebral ischemia, brain/spinal cord injury, and liver failure properties. From the previous study hWJMSCs had anticancer property. The variation of the molecules in secretome of CM is ...
Viability and cytotoxicity of hWJ-MSCs after gold nanoparticles loading.S. N. LeowChi D. LuuM. H. Hairul NizamP. L. MokR. RuhaslizanH. S. WongWan Haslina Wan Abdul HalimM. H. NgB. H. I. RuszymahS. R. Chowdhury
Confocal microscopy of the whole eye injected with hWJ-MSCs.S. N. LeowChi D. LuuM. H. Hairul NizamP. L. MokR. RuhaslizanH. S. WongWan Haslina Wan Abdul HalimM. H. NgB. H. I. RuszymahS. R. Chowdhury
This study aims to examine the antiaging potential of secretome gel (SC) from human Wharton Jelly Mesenchymal Stem Cells (hWJMSCs) in a UVB-induced mice model. Materials and Methods: The secretome was obtained from hWJ-MSCs and made in gel form. Male mic...